Particularités des abcès du foie chez l’enfant au Sénégal : description d’une série de 26 cas

Bâ, Idrissa; Ba, A.; Faye, P.M.; Diouf, Fatou; Sagna, Aloïse; Thiongane, Aliou; Diop, M.D.M.; Sow, A.I.; Fall, Ibrahima Socé; Bâ, M.

doi:10.1016/j.arcped.2016.02.018

Cited by 14 publications

(20 citation statements)

References 16 publications

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“…Nevertheless, ultrasonography is still recommended as the mainstay screening modality owing to lower cost, lack of radiation, and non-invasive properties (3). The right-lobe and solitary-lesion preponderance observed in our cases resembled prior studies, except a UK study found that 86.6% (13/15) of cases developed multiple or multiloculated abscesses (2,9,14,17,19). The mean size of the largest diameter abcess (5.3 ± 3.5 cm) among our cases was smaller, compared with prior reports in southern Taiwan (6.9), central Taiwan (6.6), and Côte-d'Ivoire (11.8) (3,9,10).…”

Section: Discussionsupporting

confidence: 86%

“…Underlying disease and predisposing host factors that have been proposed to be associated with the development of liver abscess include immunocompromised status (malignancy, malnutrition, and chemotherapy or immunosuppressant user), chronic granulomatous disease, sickle cell disease, diabetes mellitus, biliary tract anomalies, abdominal trauma, certain parasitic infections, systemic sepsis, perforated appendicitis, umbilical infection, and incorrect umbilical venous catheterization (2,10,15,16,(19)(20)(21)(22). Nevertheless, the majority of pyogenic liver abscesses are cryptogenic (2,23).…”

Section: Discussionmentioning

confidence: 99%

“…Amebic liver abscesses (ALAs) are uncommon in children, with occurrence influenced mostly by endemic factors (17). The reported incidence of ALAs for children varies, such as 7% (1/15), 30% (9/30), 35% (9/26), and 50% (10/20) from studies in Taiwan, Côte-d'Ivoire, Senegal, and Spain (3,9,19,34). Although S. aureus is the leading causal pathogen in the majority of pediatric reports, the present study reports the dominance of K. pneumoniae, paralleling three Taiwanese pediatric series (8)(9)(10)14).…”

Section: Discussionmentioning

confidence: 99%

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Pediatric Liver Abscess: Trends in the Incidence, Etiology, and Outcomes Based on 20-Years of Experience at a Tertiary Center

et al. 2020

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Background: Liver abscess is an important but relatively rare disease in children. This study investigated the clinical characteristics of eligible patients at a referral tertiary center over the past two decades. Method: A 20-year retrospective study (January 2000-December 2019) enrolled 38 children diagnosed with liver abscess. Demographic data; clinical features; laboratory, imaging, and microbiological findings; management strategy; and outcomes were reviewed from the patients' medical records. Results: Thirty-eight cases of pyogenic liver abscess were identified without a culture-proven amebic or fungal abscess. The mean age of diagnosis was 9.6 ± 6.2 years, and the male-to-female ratio was 1.92: 1. Hemato-oncological (28.9%) and predisposing hepatobiliary diseases (23.7%) were the two most common predisposing factors. Fever (94.7%) was the most common presentation followed by right upper quadrant abdominal pain (42.1%) and pleural effusion (34.2%). Among the laboratory parameters, leukocytosis was common (70.3%), and all patients had elevated serum C-reactive protein levels. Increased serum levels of alanine aminotransferase, aspartate aminotransferase, direct bilirubin, and total bilirubin were found in 40.5, 48.6, 23.1, and 42.9% of the cases, respectively. The most common pathogen in blood and pus cultures was Klebsiella pneumoniae. The mean durations of intravenous antibiotic and total antibiotic use were 29.0 ± 15.7 and 45.1 ± 22.1 days, respectively. Twelve patients (31.6%) were treated with antibiotics alone, while percutaneous needle aspiration, percutaneous pigtail drainage, and surgical intervention were performed in 12 (31.6%), 10 (26.3%), and 5 (13.2%) patients, respectively. No mortality was documented in this series. Conclusion: The present study reflects a relatively declining incidence of liver abscess compared with prior studies in Taiwan. K. pneumoniae remains the most prevalent pathogen in both blood and abscess cultures in Taiwan. Proper antimicrobial therapy with timely drainage generally yielded an adequate treatment response without any mortality.

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Section: Discussionsupporting

confidence: 86%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Pediatric Liver Abscess: Trends in the Incidence, Etiology, and Outcomes Based on 20-Years of Experience at a Tertiary Center

et al. 2020

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“…Low socioeconomic status, precarious lifestyle, anemia, and malnutrition have been found to be predisposing factors of LA. 3 As mentioned in literature, most of the patients in this series had PLA (84%). This is close to what is reported in literature.…”

Section: Discussionmentioning

confidence: 90%

“…Other studies have also found nearly same ratio. 3 The exact reason for more occurrence in male children is unknown.…”

Section: Discussionmentioning

confidence: 99%