Particle size determination by quasielastic light scattering

McConnell, M. L.

doi:10.1021/ac00231a003

Cited by 16 publications

(5 citation statements)

References 12 publications

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“…A limiting case of inelastic scattering may also exist where the frequency change upon scattering is small compared to the incident energy known as “quasi-elastic scattering (QELS)” regime. QELS is often used as a particle size characterization tool 13 .…”

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confidence: 99%

Ultrasensitive and fast detection of denaturation of milk by Coherent backscattering of light

Verma

Singh

Senthilkumaran

et al. 2014

Sci Rep

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In this work, Coherence backscattering (CBS) of light has been used to detect the onset of denaturation of milk. The CBS cone shape and its enhancement factor are found to be highly sensitive to the physical state of the milk particles. The onset of denaturing of milk not visible to the naked eye, can be easily detected from changes in the CBS cone shape. The onset of denaturation is confirmed by spectral changes in Raman spectra from these milk samples. Further, the possibility to estimate the dilution of milk by water as an adulterant is demonstrated. The method reported has a broad scope in industry for making an inline ultrafast cost effective sensor for milk quality monitoring during production and before consumption.

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mentioning

confidence: 99%

Ultrasensitive and fast detection of denaturation of milk by Coherent backscattering of light

Verma

Singh

Senthilkumaran

et al. 2014

Sci Rep

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“…The proposed method can also be utilized for 3D visualization of near-field enhancement of plasmonic nanostructures. 46 Particle light scattering is a well-known phenomenon and historically has been used to determine particle size distribution in colloidal solutions 47 and to study aerosols in the atmosphere, 48 but in this work, they are employed for 3D lithography.…”

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confidence: 99%

Three-Dimensional Nanolithography Using Light Scattering from Colloidal Particles

2013

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The interaction between light and colloidal elements can result in a wealth of interesting near-field optical patterns. By examining the optical and colloidal properties, the intensity distribution can be tailored and harnessed for three-dimensional nanolithography. Here, we examine the use of light scattering from colloidal particles to fabricate complex hollow nanostructures. In this approach, a single colloidal sphere is illuminated to create a scattering pattern, which is captured by a photoresist in close proximity. No external optical elements are required, and the colloidal elements alone provide the modulation of the optical intensity pattern. The fabricated nanostructures can be designed to have multiple shells, confined volumes, and single top openings, resembling "nano-volcanoes." The geometry of such structures is dependent on the scattered light distribution and can be accurately modeled by examining the light-particle interaction. The hollow nanostructures can be used to trap nanomaterial, and we demonstrate their ability to trap 50 nm silica nanoparticles. These well-defined surface hollow structures can be further functionalized for applications in controlled drug delivery and biotrapping. Colloidal elements with different geometries and material compositions can also be incorporated to examine other light-colloid interactions.

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“…Photon Correlation Spectroscopy. The hydrodynamic size of macromolecules can be estimated through the use of a laser light scattering technique known alternatively as photon correlation spectroscopy (PCS), dynamic light scattering (DLS), or quasielastic light scattering (QELS) (53). PCS can be used to monitor protein denaturation (54) due to an ability to detect variations in hydrodynamic size.…”

Section: Quaternary Structurementioning

confidence: 99%

Investigations of protein structure with optical spectroscopy: bovine growth hormone

Havel¹,

Chao²,

Haskell³

et al. 1989

Anal. Chem.

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Optical spectroscopy provides a wealth of information about protein structure that is difficult to obtain from other methods. Investigations of changes in primary, secondary, tertiary, and quaternary structure are particularly well-suited for optical techniques such as UV absorption, circular dichroism, fluorescence, Raman and infrared spectroscopy, as well as light scattering methods. Each method has unique areas of applicability and contributes to structure determination in a different manner. The application of these methods is demonstrated with examples of studies performed on bovine growth hormone. Some of these include: determination of solution-state structure, monitoring differences between solution- and solid-state structure, determination of molecular size distribution, and investigations of protein folding mechanisms. It is demonstrated that by judicious choice of methods, a reasonably complete description of protein structure can be obtained.

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Particle size determination by quasielastic light scattering

Cited by 16 publications

References 12 publications

Ultrasensitive and fast detection of denaturation of milk by Coherent backscattering of light

Ultrasensitive and fast detection of denaturation of milk by Coherent backscattering of light

Three-Dimensional Nanolithography Using Light Scattering from Colloidal Particles

Investigations of protein structure with optical spectroscopy: bovine growth hormone

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