The measurement of energetic particles plays an important role in the space environment monitoring and space weather forecasting. The accuracy of the energetic electron measurement is seriously influenced by the proton contamination. An anti-proton contamination design for the sensor of imaging energetic electron spectrometer is introduced in this paper. According to the electron and proton spectrum on the typical satellite orbits calculated by the radiation belt models, the efficiency of the anti-proton contamination design is estimated by the Geant4 simulation and the design is optimized based on the simulation results. energetic particle measurement, imaging energetic electron spectrometer, anti-proton design, Geant4 simulation Citation: Luo L, Zou H, Zong Q G, et al. Anti-proton contamination design of the imaging energetic electron spectrometer based on Geant4 simulation. Sci