Participation rates in Epidemiologic studies

Ramos, Pedro Lima; Santana, Regina Helena Carlucci; Cima, Joana; Marques, Ana Patrícia; Baptista, António M. G.; Moreno, Laura Hernández; Macedo, António Filipe

doi:10.1093/eurpub/ckv176.008

Cited by 4 publications

(3 citation statements)

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“…As participants of higher compliance and social inclusion are more likely to take part in that kind of study [65], a shift toward subjects that show higher socioeconomic status scores could potentially appear and could therefore limit the representativity of the study. However, the effect of the latter is minimal because age, Tanner stage, and hormone levels do not show a correlation with social background.…”

Section: Discussionmentioning

confidence: 99%

The Influence of Steroid Hormones on Tooth Wear in Children and in Adolescents

Buchhardt

Kieß²,

Körner³

et al. 2022

JCM

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(1) Background: From a young age, boys are more often affected by tooth wear than girls. This suggests an influence of the male sex hormone (testosterone) on the aetiology of tooth wear. The aim of the present study was to investigate the incidence of tooth wear in relation to steroid hormone levels in children. (2) Methods: 1022 test persons aged between 10 and 18 (491 male, 531 female) from the LIFE Child study underwent medical and dental examination. Tooth wear was measured through clinical inspection. Blood samples were taken to determine hormone levels (testosterone, SHBG). The level of free testosterone was calculated from the ratio of testosterone to SHBG. Using multivariable methods, the incidence of tooth wear was analyzed as a function of hormone levels, while controlling for confounders such as age, sex, social status, and orthodontic treatment. () Results: The incidence of tooth wear increased with age in both sexes. Boys showed significantly more often attrition facets than girls (17.5% vs. 13.2%, p < 0.001). Subjects with tooth wear showed significantly higher free testosterone levels than those without (males: p < 0.001, females: p < 0.05). After controlling for confounding variables, the risk of tooth wear increased by approximately 30.0% with each year of life (odds ratio [OR]boys = 1.29, 95% confidence interval [CI] = 1.04–1.56; [OR]girls = 1.32, 95% CI = 1.08–1.61). In addition, the risk of tooth wear increased by 6.0% per free testosterone scale score only in boys (OR = 1.06, 95% CI = 1.01–1.12). (4) Conclusions: Tooth wear is common in children and in adolescents, and it increases steadily with age in both sexes. The stronger increase and the higher prevalence among male adolescents can be explained by the additional effect of free testosterone.

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Section: Discussionmentioning

confidence: 99%

The Influence of Steroid Hormones on Tooth Wear in Children and in Adolescents

Buchhardt

Kieß²,

Körner³

et al. 2022

JCM

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“…In fact, the well-known obsolescence of dementia-related epidemiological data in Europe 5 is due to a decrease in participation rates in epidemiological studies over the past 30 years, which has witnessed an even steeper decline in more recent years. 6,7 The success of population studies depends on the voluntary participation of individuals who donate their time and their personal health information, often accepting a certain degree of risks to their welfare. Therefore, researchers should take into account legitimate expectations of individuals to receive some personal gain from participation, such as research results or information on their health.…”

Section: Introductionmentioning

confidence: 99%

“…Effective progress in this area also depends on the promotion of participation in research. In fact, the well‐known obsolescence of dementia‐related epidemiological data in Europe 5 is due to a decrease in participation rates in epidemiological studies over the past 30 years, which has witnessed an even steeper decline in more recent years 6,7 . The success of population studies depends on the voluntary participation of individuals who donate their time and their personal health information, often accepting a certain degree of risks to their welfare.…”

Section: Introductionmentioning

confidence: 99%

Returning individual‐specific results of a dementia prevalence study: insights from prospective participants living in Switzerland

Fadda

Fiordelli

Amati

et al. 2020

Int J Geriat Psychiatry

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Funding information Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung, Grant/ Award Number: 320030_184794 Objectives: To explore prospective participants' preferences regarding the return of their individual-specific results from a dementia prevalence study (a probabilistic diagnosis of dementia). Methods/Design: We conducted a qualitative study with 22 individuals aged 45 to 86 and resident in the Canton of Ticino (Switzerland). Participants had previously joined the validation phase of an epidemiological study into dementia and its impact. Results: We found that individuals welcome the return of their individual-specific results, provided these meet a number of validity, clinical, and personal utility criteria. They justify researchers' duty to return study findings with the principles of beneficence (eg, providing information that can help participants' medical decision-making) and justice (eg, acknowledging participants' efforts to help research by sharing their personal information). Furthermore, individuals anticipate societal benefits of the return of individual specific study findings, including improved interpersonal relationships among individuals and decreased dementia-related stigma. Conclusions: Our findings suggest that researchers should address the return of individual-specific study results early on during study design and involve prospective participants in identifying both the conditions under which results should be offered and the perceived individual and societal benefits returning can have.

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