Partially fluorinated alkanes as wash out solutions after removal of silicone oil used as an ocular endotamponade

Abstract

Since the solubility of silicone oil in F(6)H(8) or O(44 V) is dependent on the temperature and mixture ratio, their use as a routine washout after silicone oil removal in patients without severe emulsification is inefficient. The degree of washout is strongly influenced by surface phenomena and adhesion forces.

Chemistry, Physical Chemistry, and Uses of Molecular Fluorocarbon−Hydrocarbon Diblocks, Triblocks, and Related Compounds—Unique “Apolar” Components for Self-Assembled Colloid and Interface Engineering

“…Whether specific gravity was the reason for retinal degeneration in long-term tamponade with F 6 H 8 has been questioned. , There was no evidence that higher density led to more pronounced side effects in the series F 4 H 4, F 6 H 2, F -octane, and F -decalin (densities of 1.24, 1.62, 1.78, and 1.92, respectively) . Liquid diblocks have also been used as intraocular washes to remove residual silicone oil from intraocular silicon lenses or after silicone oil tamponade, , although their efficacy has been questioned, and for the flotation and removal of dislocated intraocular lens components. A series of semifluorinated symmetrical diethers, CF 3 CH 2 O(CH 2 ) 3−10 OCH 2 CF 3 , provided material that had a chemical inertness, O 2 solubility, and transparency close to those of F Cs, but with substantially lower and adjustable specific gravity (1.06−1.23 g cm −3 ); the biocompatibility results were, however, disappointing.…”