Partial unilateral lentiginosis associated with nevus of Ota

González‐Sixto, B.; Torre, Carlos de la; Posada, Celia; Sevillano, C.

doi:10.1016/j.jaad.2009.04.049

Cited by 3 publications

(2 citation statements)

References 4 publications

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“…In two instances, malignant melanoma (MM) grew within the involved skin . Other than the coincidental association with common multifactorial diseases, lentigines arranged in a checkerboard pattern rarely co‐occurred with other mosaic conditions (achromic naevus, Becker naevus, Ota naevus or linear atrophoderma).…”

Section: Lentiginesmentioning

confidence: 99%

Melanocytic naevi clustered on normal background skin

Torchia

2015

Clin Exp Dermatol

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Several types of maculopapular melanocytic naevi can occur in a multiple form, and be arranged in a nonrandom fashion on the skin. The most frequently reported segmentally grouped naevi are lentigines. Two types of segmentally arranged lentigines probably exist. The first is associated with neurofibromatosis (NF)1 or NF1 signs, features scattered light-brown lesions and can be considered a type of mosaic NF1. By contrast, non-NF1 associated lesions are characterized by densely packed, dark lesions, and can be defined as 'non-NF1 checkerboard-arranged lentigines'. Blue naevi, Spitz naevi and common acquired melanocytic naevi can occur, clustered in an agminated (or cannonball) shape. However, if large enough, they always follow a checkerboard pattern. Hence, such mosaic conditions should be termed 'checkerboard-arranged blue naevi', 'checkerboard-arranged Spitz naevi' and 'checkerboard-arranged common acquired melanocytic naevi'. Segmentally arranged dysplastic melanocytic naevi probably represent a mosaic form of dysplastic naevus syndrome. Dysplastic melanocytic naevi confined to a cutaneous segment could be defined as 'isolated segmental dysplastic naevus syndrome', while segmentally arranged dysplastic melanocytic naevi co-occurring with widespread, nonsegmental dysplastic melanocytic naevi might configure a 'superimposed segmental dysplastic naevus syndrome'. Small congenital melanocytic naevi are always grouped along Blaschko lines. The only other instances following Blaschko lines are the so-called 'linear lentiginous naevus' and a unique case of multiple deep penetrating naevi.

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Section: Lentiginesmentioning

confidence: 99%

Melanocytic naevi clustered on normal background skin

Torchia

2015

Clin Exp Dermatol

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“…Neurologic, endocrinological, or hematological disorders can be associated with this disorder, although most patients do not exhibit any abnormalities. 1,[3][4][5][6][7] Moreover, there has been a debate whether or not PUL is a form of segmental neurofibromatosis (NF) type 1. 1,8 Whereas PUL cases were scarce in Caucasians, these were reportedly common in specific regions including Korea, Japan, Turkey, India, and Spain.…”

Section: Introductionmentioning

confidence: 99%

Partial unilateral lentiginosis: a clinicopathological analysis of 32 cases on the head and neck area in Korea

Kim

Choi

et al. 2021

Int J Dermatology

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Background Partial unilateral lentiginosis (PUL) is a rare acquired circumscribed hyperpigmentation characterized by multiple simple lentigines involving half of the body.Since the previous studies of PUL were mostly based on case reports and the current literature lacks well-designed retrospective studies that involve a large number of cases, PUL is not a well-defined entity, and differential diagnosis with nevus spilus is still difficult.This study aims to evaluate clinical and histopathological characteristics and treatment outcomes of PUL on head and neck area of Koreans. Methods Thirty-two patients with PUL on head and neck area were diagnosed clinicohistopathologically at the Asan Medical Center from 2004 to 2017. Their medical records, photographs, and biopsy specimens were reviewed, and immunohistochemical staining for protein kinase C (PKC)-bΙΙ was evaluated for melanogenic activity.Results Four patients (12.5%) of PUL had congenital lesions, and 24 (75.0%) had age of onset younger than 10 years. Confluency of lentiginous lesions (100%) and mild to moderate background interlesional hyperpigmentation (90.6%) were observed. The lentiginous lesions showed increased melanocytes, melanophages, basal melanins, lentiginous hyperplasia, and perivascular inflammatory cells compared with background interlesional hyperpigmentation, and PKC-bΙΙ was focally positive in 7 of 12 stained PUL lesions. Among the 16 patients who received laser treatments, 10 (62.5%) showed more than 50% of improvement.Conclusions The findings of this study will allow for improved diagnosis of PUL and understanding of its features, which may facilitate proper management in the future.

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Partial Unilateral Lentiginoses

Grynszpan¹

2015

Pigmentary Disorders

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Partial unilateral lentiginosis associated with nevus of Ota

Cited by 3 publications

References 4 publications

Melanocytic naevi clustered on normal background skin

Melanocytic naevi clustered on normal background skin

Partial unilateral lentiginosis: a clinicopathological analysis of 32 cases on the head and neck area in Korea

Partial Unilateral Lentiginoses

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