Partial thyroidectomy for thyrotoxicosis

Gough, A L; Neill, Richard

doi:10.1002/bjs.1800611203

Cited by 19 publications

(7 citation statements)

References 14 publications

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“…Where both levels are above 4 pg per cent all the patients are euthyroid, and the risk of developing hypothyroidism subsequently is negligible. The definition of postoperative hypothyroidism at an early date is in accord with the experience of others (Olsen et al, 1970;Caswell and Maier, 1972), and may suggest that when a rising incidence is recorded over several years (Nofal et al, 1966;Gough and Neill, 1974), a lower index of clinical suspicion of clinical features of hyperthyroidism and increased sympathetic activity has been recognized. Sympathetic blockade is not a new concept.…”

Section: Hypothyroidismsupporting

confidence: 59%

Whither thyrotoxicosis?

Michie

1975

Journal of British Surgery

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For 30 years the thyrotoxic patient has been subjected to a plurality of treatments by surgery, radio-iodine and long term anti-thyroid drugs. These therapies have been accepted as complementary to the needs of the individual patient, without regard for long term results or the economic situation as it affects both patient and hospital services. In the context of surgical treatment which is now available, it is suggested that the advantages of operation over other therapies presage a reversion to surgery as the treatment of choice.

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Section: Hypothyroidismsupporting

confidence: 59%

Whither thyrotoxicosis?

Michie

1975

Journal of British Surgery

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“…Neither recurrence nor the incidence of hypothyroidism correlated with age, sex, or size of gland (7,10,20,21,29), though in one study there was a correlation between weight over 100 g and recurrence (20,30).…”

Section: Discussionmentioning

confidence: 91%

“…The long term results after subtotal thyroidectomy show that euthyroidism may be achieved in about 60% of patients, while hypothyroidism and recurrence rarely exceed 20%-30% and 2%-15%, respectively (5,14,17,18,22). Neither a predictive index of activity of the disease nor a particular surgical technique can guarantee euthyroidism postoperatively (3,5,7,10,12,14,16,19,21,26,29). Some authors have suggested that total thyroidectomy is the definitive treatment of Graves' disease, given that it avoids recurrence and the high rate of complications associated with reoperation (15,23).…”

Section: Introductionmentioning

confidence: 99%

Is euthyroidism the goal of surgical treatment of diffuse toxic goitre?

et al. 2003

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“…In previous reports, hypothyroidism following subtotal thyroidectomy was 10% to 30% [2][3][4][5][6]. The recurrence rate was 5% to 6% [5,7].…”

Section: Discussionmentioning

confidence: 98%

Clinical course and thyroid stimulating hormone (TSH) receptor antibodies during surgical treatment of Graves' disease

et al. 1992

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This study assessed the results of surgical treatment for Graves' disease in our hospital and examined the relationship between the values of thyroid stimulating hormone (TSH) receptor antibodies and postoperative thyroid function. From 1983 to 1988, subtotal thyroidectomy was performed in 313 patients with Graves' disease. The follow-up rate was 89.1% (278 of 313 patients). Thirteen (4.2%) patients required methimazole postoperatively for hyperthyroidism and 23 (7.3%) patients required L-thyroxine postoperatively for hypothyroidism. The relationship between the postoperative thyroid function and TSH receptor antibodies was examined. The pre-operative thyrotropin binding inhibitory immunoglobulin (TBII) value had no relationship to postoperative thyroid function. Only in the patients who were hyperthyroid postoperatively did the TBII value remain elevated, but the value decreased gradually in patients who were not hyperthyroid postoperatively. In 43 of 94 patients whose pre-operative TBII values were high, the postoperative TBII value normalized. The higher the preoperative TBII value, the longer time was required for it to normalize postoperatively. The postoperative thyroid stimulating antibody (TSAb) values were higher in patients who remained hyperthyroid than in the patients who were not hyperthyroid. In the patients who remained hyperthyroid postoperatively, there was a significant correlation between the postoperative TBII value and the TSAB value. In the patients who were hypothyroid postoperatively, the TSBAb values were negative. In patients undergoing surgical treatment of Graves' disease, the postoperative TBII and TSAb values were related to postoperative hyperthyroidism. The TSBAb value had no relationship to postoperative hypothyroidism.

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Partial thyroidectomy for thyrotoxicosis

Cited by 19 publications

References 14 publications

Whither thyrotoxicosis?

Whither thyrotoxicosis?

Is euthyroidism the goal of surgical treatment of diffuse toxic goitre?

Clinical course and thyroid stimulating hormone (TSH) receptor antibodies during surgical treatment of Graves' disease

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