Partial laryngectomy in glottic cancer: complications and oncological results

Graciano, Agnaldo José; Sonagli, Marina; Silva, Ana Gabriela Clemente da; Fischer, Carlos Augusto; Chone, Carlos Takahiro

doi:10.1016/j.bjorl.2015.05.011

Cited by 8 publications

(9 citation statements)

References 26 publications

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“…A series of 120 patients underwent partial laryngectomy from January, 1996 to July, 2014 at the Departments of Head and Neck Surgery, Hospital Ana Costa, Santos and Irmandade da Santa Casa da Misericórdia de Santos, Santos, Brazil, with the following indication protocol [2], according local staging (T):…”

Section: Methodsmentioning

confidence: 99%

“…Laryngeal cancer shows unique treatment considerations due to the vital role of the larynx in human communication, deglutition and quality of life [1]. It varies in incidence throughout different geographical regions, being more common in Southern Europe (10.9-100,000), Eastern Europe (9.2-100,000) and South America (7.2-100,000) and more prevalent in men [2], corresponding to 2.5% of all tumors in men, representing the sixth most common malignancy in men in Brazil [3]. Since Billroth performed, in 1874, the first total laryngectomy [4], there has been great progress in laryngeal cancer surgery, mainly in its technique, culminating in the partial laryngectomies.…”

Section: Introductionmentioning

confidence: 99%

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Results of the Conservative Surgery for Laryngeal Cancer

Silva¹,

Ortiz²,

Aparecido³

2017

Otolaryngol Res Rev

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Introduction:The techniques of partial laryngectomy are based on the compartimentalization of the larynx and their aims are to provide the oncologically radical excision and to preserve the laryngeal function.Objective: To evaluate the oncological results and the complications in patients submitted to these techniques. Methods: A consecutive series of 120 patients underwent partial laryngectomy from 1996 to 2016, according to the local clinical staging (T). The surgical margins were evaluated for frozen section examination during the surgery. The follow up varied from 4 to 120 months (median, 48.5). Adjuvant radiation therapy was indicated according to the lymph node staging (pN+). The following complications were evaluated: edema of the arytenoid, pharyngocutaneous or laryngocutaneous fistula, pneumonia, haemorrhage, dysphagia, wound infection, laryngeal stenosis and glottic insufficiency. Results:The free of disease survival was: 84.6% for T1 tumors; 84.5% for T2; and 40% for T3. After the surgical salvage, the ultimate survival was: 97% for T1; 92.9% for T2; and 40% for T3. There was edema of the arytenoid in 7 patients, laryngocutaneous fistula in 4; wound infection in 3; pneumonia in 5; dysphagia in 1; and laryngeal stenosis in 6. Conclusions:The global disease free survival rate after treatment was of 84,6% in T1, 84,5% in T2 and 40% in T3, with better results in earlier staged tumors. Complications incidence is acceptable and can be treated conservatively.

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Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Results of the Conservative Surgery for Laryngeal Cancer

Silva¹,

Ortiz²,

Aparecido³

2017

Otolaryngol Res Rev

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“…This is a common practice, as the device allows regulation of the upper airways, which in laryngeal cancer are affected by cancer cells. Thus, this is a means of providing satisfactory respiratory support to the patient, but, as adverse effects, oral communication is hindered [22,23].…”

Section: Discussionmentioning

confidence: 99%

Radiotherapy Symptoms in Head and Neck Cancer Patients in Northeast Brazil

Horta¹,

Oliveira²,

Oliveira³

et al. 2020

COR

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Objective: To describe the symptoms of radiotherapy in head and neck cancer patients and the time of initial onset of those. Material and Methods: All ethical precepts were followed, and the present study was approved by CEP number 92772318.8.0000.5546. The data collection in 41 head and neck cancer patients were performed by applying a questionnaire adapted by the researchers based on the EORTC QLQ-H & N35 protocol. The questionnaire consisted of 19 closed questions focusing on the adverse effects ofradiotherapy. Results: Most participants were male, with laryngeal cancer being the one with the highest incidence. Among the deleterious symptoms, the ones with more occurrence were weight loss, xerostomia, dysphagia and use of catheters. They appeared at the beginning of treatment, between the 6th and 10th session of radiotherapy. Symptoms such as social/family difficulties and oral communication had been present since the beginning of the treatment, extending to those who had completed the therapeutic procedure. Conclusion: Adverse symptoms are common in patients undergoing radiotherapy treatment for head and neck cancer, and mostly include aspects related to the eating process with involvement at the beginning of the treatment.

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“…The relationship between the base and the tongue and the vestibule is not disturbed, and one intact side of the larynx retains its sphincter function. Patients with vertical partial laryngectomy do not have significant swallowing problems (7,18). Swallowing problems in subtotal laryngectomies are pronounced.…”

Section: Partial Laryngectomiesmentioning

confidence: 99%

“…Two primary approaches to the treatment of laryngeal cancer are surgical treatment and radiotherapy and they can be combined. Primary radiotherapy is less destructive to tissue and can be used in early glottic cancer (7). If the tumor is in the earliest stage, there are almost no side effects, but if there is a larger amount of radiotherapy (6,000-7,000 Gy), the side effects of radiotherapy are related to phonation and swallowing problems due to xerostomia, mucosal damage, thick saliva, loss of sense of taste and smell, edema, inflammatory processes of the gums and oral cavity.…”

Section: Introductionmentioning

confidence: 99%

Swallowing disorders during and after the treatment of larynx cancer

Zelić¹,

Petrović-Lazić²,

Pavlović³

2021

Medicinski časopis

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Dysphagia is a swallowing disorder that is characterized by difficulty to swallow and to control saliva as well as by feeding difficulties. Dysphagia is a common symptom of laryngeal cancer, or a consequence of surgical treatment as well as radiotherapy and chemotherapy of this neoplasma. The patients after laryngectomy are at risk of developing malnutrition, and aspiration pneumonia. Removal of anatomical structures and reorganization of remaining tissues has a significant impact on the physiology of swallowing. For most patients, safe swallowing is the main feature of a positive treatment outcome. Swallowing therapy is important before, during and after treatment of larynx cancer. The aim of this paper is to explore a correlation between swallowing disorders and laryngeal cancer treatment, and to understand the anatomical and physiological bases of dysphagia treatment.

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Partial laryngectomy in glottic cancer: complications and oncological results

Abstract: Open partial laryngectomy had complication rates and oncological results similar to those of radiotherapy for patients with glottic carcinomas and should still be considered among the main available therapeutic options.

Cited by 8 publications

References 26 publications

Results of the Conservative Surgery for Laryngeal Cancer

Results of the Conservative Surgery for Laryngeal Cancer

Radiotherapy Symptoms in Head and Neck Cancer Patients in Northeast Brazil

Swallowing disorders during and after the treatment of larynx cancer

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