Partial Compliance and Risk of Rehospitalization Among California Medicaid Patients With Schizophrenia

Weiden, Peter J.; Kozma, Chris M; Grogg, Amy; Locklear, Julie

doi:10.1176/appi.ps.55.8.886

Cited by 559 publications

(422 citation statements)

References 23 publications

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“…Studies consistently showed that nonadherence was significantly associated with poorer outcomes, including greater risk of hospitalization [Ahn et al 2008;Eaddy et al 2005;Gilmer et al 2004;Law et al 2008;Morken et al 2008;Svarstad et al 2001;Valenstein et al 2002;Weiden et al 2004a], greater use of emergency services , longer length of hospital stay Valenstein et al 2002] and greater risk of suicide [Leucht and Heres, 2006;Llorca, 2008]. The consequences to society included having to deal with the consequences of violence , substance abuse and criminal behaviour .…”

Section: Discussionmentioning

confidence: 99%

Medication adherence in schizophrenia: factors influencing adherence and consequences of nonadherence, a systematic literature review

Higashi¹,

Medic

Littlewood

et al. 2013

Therapeutic Advances in Psychopharmacology

476

381

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Background: Nonadherence to medication is a recognized problem and may be the most challenging aspect of treatment. Methods:We performed a systematic review of factors that influence adherence and the consequences of nonadherence to the patient, healthcare system and society, in patients with schizophrenia. Particular attention was given to the effect of nonadherence on hospitalization rates, as a key driver of increased costs of care. A qualitative systematic literature review was conducted using a broad search strategy using disease and adherence terms. Due to the large number of abstracts identified, article selection was based on studies with larger sample sizes published after 2001. Thirty-seven full papers were included: 15 studies on drivers and 22 on consequences, of which 12 assessed the link between nonadherence and hospitalization. Results: Key drivers of nonadherence included lack of insight, medication beliefs and substance abuse. Key consequences of nonadherence included greater risk of relapse, hospitalization and suicide. Factors positively related to adherence were a good therapeutic relationship with physician and perception of benefits of medication. The most frequently reported driver and consequence were lack of insight and greater risk of hospitalization respectively. Conclusions: Improving adherence in schizophrenia may have a considerable positive impact on patients and society. This can be achieved by focusing on the identified multitude of factors driving nonadherence.

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Section: Discussionmentioning

confidence: 99%

Medication adherence in schizophrenia: factors influencing adherence and consequences of nonadherence, a systematic literature review

Higashi¹,

Medic

Littlewood

et al. 2013

Therapeutic Advances in Psychopharmacology

476

381

View full text Add to dashboard Cite

show abstract

“…조현병 환자가 약물치료를 중단한 경우, 그 기간이 길수록 증상 악화 및 재발로 인한 입원 의 위험이 증가하였다 [7]. 양극성 장애 환자 중 약물순응도가 낮은 환자는 높은 환자에 비해 자살률이 5.2배나 높은 것으로 보고되었다 [8].…”

Section: 정신질환 대상자들이 치료에 잘 순응하지 않음으로 인한 문 제는 증상악화 재발률 증가 입원율 증가 등이 있unclassified

Mediating Effect of Self-Efficacy in the Relationship between Internalized Stigma and Treatment Adherence of Community Dwelling Patients with Mental Illness

Kim

2016

J Korean Acad Psychiatr Ment Health Nurs

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Purpose: This study was conducted to explore the mediating effect of self-efficacy in the relationship between internalized stigma and treatment adherence among community dwelling patient with mental illness. Methods: A cross-sectional study design was employed. Participants were 145 people with mental illness who were enrolled at one of 11 community mental health institutions in Busan, South Korea. Internalized stigma of mental illness, self-efficacy, treatment adherence, and socio-demographic data were examined. Data were collected using self-report questionnaires and analyzed using Baron and Kenny method. Results: Internalized stigma had a significant negative correlation with self-efficacy and treatment adherence. Self-efficacy had a significant positive correlation with treatment adherence. In addition, self-efficacy had a full mediating effect in the relationship between internalized stigma and treatment adherence. Conclusion: The results suggest that self-efficacy plays an important role in promoting treatment adherence among patients with mental illness who have high levels of internalized stigma. Therefore, mental health professionals should focus on reducing internalized stigma and also enhancing self-efficacy to increase treatment adherence for persons with mental illness living in the community.

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“…Antipsikotik ilacın kullanılmasının sürdürülememesi; tedavi başarısızlığı, hastaneye yatış ve artmış intihar sıklığı gibi ciddi sonuçlara yol açabilir. Şizofreni hastalarının %50'si reçetelenen tedaviye uyum gösteremezler (15,(17)(18)(19). Şizofreni veya şizoaf-fektif bozukluğu olan hastalarda günlük doz sıklığı tedavi uyumsuzluğunda anlamlı bir öngördürücüdür (20).…”

Section: şEkil 1: Plazma Konsantrasyonu -Zaman Grafiğiunclassified

Tedavide Hızlı Salınımlı ve Uzatılmış Salınımlı Formülasyonların Farkları

Üresin

Baran

2011

Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychophar

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Partial Compliance and Risk of Rehospitalization Among California Medicaid Patients With Schizophrenia

Abstract: This study showed a direct correlation between estimated partial compliance and hospitalization risk among patients with schizophrenia across a continuum of compliance behavior.

Cited by 559 publications

References 23 publications

Medication adherence in schizophrenia: factors influencing adherence and consequences of nonadherence, a systematic literature review

Medication adherence in schizophrenia: factors influencing adherence and consequences of nonadherence, a systematic literature review

Mediating Effect of Self-Efficacy in the Relationship between Internalized Stigma and Treatment Adherence of Community Dwelling Patients with Mental Illness

Tedavide Hızlı Salınımlı ve Uzatılmış Salınımlı Formülasyonların Farkları

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