Parthenium Hysterophorus. L. (Asteraceae) : A Boon or Curse? (A Review)

Joshi, Adarsh; Bachheti, Rakesh Kumar; Sharma, Ashutosh; Mamgain, Ritu

doi:10.13005/ojc/320302

Cited by 12 publications

(5 citation statements)

References 50 publications

(56 reference statements)

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Section: Discussionmentioning

confidence: 88%

“…A novel hydroxyproline-rich glycoprotein has been documented from the pollen of P. hysterophorus [7]. Another novel sesquiterpenoid, charminarone, has also been previously reported [8][9][10]. On the basis of the abovementioned information, there is a need to fully explore the medicinal potential of P. hysterophorus, and to extract and isolate more active phytochemicals that rationalize its properties and pharmaceutical applications.…”

Section: Introductionmentioning

confidence: 96%

See 1 more Smart Citation

Phytochemical Analysis and In Vitro and In Vivo Pharmacological Evaluation of Parthenium hysterophorus Linn

Gul

Khan

Alnasser

et al. 2022

Evidence-Based Complementary and Alternative Medicine

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The main aim of this research was to explore Parthenium hysterophorus Linn phytochemically and pharmacologically. Phytochemical screening is important for the isolation of active compounds before bulk extraction. The crude extracts and their fractions were screened for enzyme (urease, α-glycosidase, and phosphodiesterase) inhibition assays, in vivo analgesic, anti-inflammatory, and sedative effects. Results indicated the presence of steroids, flavonoids, etc. The crude extracts such as methanol, hexane, aqueous, ethyl acetate, chloroform, and butanol exhibited excellent urease inhibitory activities with IC50 = 43.1 ± 1.24, 31.9 ± 2.21, 31.9 ± 2.21, 57.3 ± 1.27, 49.2 ± 2.16, and 35.3 ± 1.12, respectively, as compared to standard acetohydroxamic acid (20.3 ± 0.43). The extracts (methanol, hexane, aqueous, ethyl acetate, chloroform, and butanol) also showed promising α-glycosidase potency with IC50 = 13.1 ± 0.34, 21.2 ± 1.16, 23.1 ± 0.12, 84.2 ± 2.17, 118.6 ± 3.07, and 840 ± 1.73, respectively against acarbose (840 ± 1.73). The phosphodiesterase activity of the mentioned extracts was also excellent with IC50 = 131.1 ± 2.41, 197.2 ± 3.16, 24.2 ± 0.11, 62.4 ± 2.21, 152.4 ± 1.81, and 55.3 ± 2.15, respectively, against the standard (265.5 ± 2.25). Furthermore, butanol (14.96 ± 1.78), ethyl acetate (18.98 ± 1.71), and methanol (16.87 ± 1.00) showed dose-dependent analgesic effects with a maximum inhibition of acetic acid-induced writhes. Whereas, methanolic and butanol extracts exhibited maximum inhibition of inflammation in the carrageenan paw edema test. The aqueous ( p < 0.01 ) and butanol ( p < 0.01 ) extracts exhibited maximum a sedative effect followed by chloroform ( p < 0.05 ), ethyl acetate ( p < 0.05 ), and methanolic ( p < 0.05 ) fractions as compared to the standard drug. The current research concluded that Parthenium hysterophorus Linn has important phytochemical constituents having inhibitory effects on urease, α-glycosidase, and phosphodiesterase enzymes. Furthermore, the plant has analgesic, anti-inflammatory, and sedative effects. The P. hysterophorus needs to further be explored for the candidate molecules responsible for the abovementioned activities.

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Section: Discussionmentioning

confidence: 88%

Section: Introductionmentioning

confidence: 96%

Phytochemical Analysis and In Vitro and In Vivo Pharmacological Evaluation of Parthenium hysterophorus Linn

Gul

Khan

Alnasser

et al. 2022

Evidence-Based Complementary and Alternative Medicine

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“… This weed has also been used for the removal of heavy metals as this can be used as plant extract and it helps in removing the toxicity of metals in an area where the soil is contaminated by metals and dyes and therefore can minimize the risk of toxic metals entering into the food chain of animals (Joshi et al, 2016).  Parthenium also have the capacity in treating the allergy caused by the plant itself, by using the drug extract from the plant.…”

Section: Beneficial Aspects Of Partheniummentioning

confidence: 99%

Parthenium hysterophorus Being Boon and Bane for Human Beings: A Review

Nishtha¹,

Rana²

2022

BKAP

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Talking about the invasive species of plants there are many of them like Ageratum conyzoides, Cannabis sativa, Parthenium hysterophorus, Lantana camara, Tribulus terrestris and many more. And one of these is Parthenium hysterophorus which we will be discussing in this paper. P. hysterophorus is native species to tropical America, Mexico and the southern USA. This invasive plant belongs to the Asteraceae family. This is said to be a poisonous annual herb that grows aggressively. It has certain harmful effects on agriculture, livestock and human life. This herb tends to cause skin problems, respiratory problems, fever and bronchitis-like problems in humans. Despite having many harmful elements this weed is also known to have health benefits examples as urinary tract infection, rheumatic pain and Diarrhoea. This herb is spreading all over India badly. Certain experiments and methods are being done on this plant to know the impactful parameters of the plant which can be used in a productive way. It has the potential to be used as bio-pesticides and for removing heavy metals and dyes. In this paper, we have discussed this noxious herb and its benefits. The goal of the review is to impart basic knowledge about, morphology, discovery, harmful and beneficial effects, active compounds and preventive measures about P. hysterophorus.

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“…The plant grows about 30-90 cm in height, but up to 1.5 m, or 2.5 m, in exotic situations and reproduces through seed [11, 12]. It is locally utilized as a home-grown solution for different intestinal and skin issues, treatment of wounds, ulcerated injuries, fever, heart issues, toothaches, bubbles and pimples treatment, fevers, against a sleeping disorder and to treat diabetes [13,14]. During this study fresh and dry plants was used to make extracts and investigate its antibacterial potential against common bacterial isolates.…”

Section: Introductionmentioning

confidence: 99%

Antimicrobial activity of Parthenium hysterophorus against five bacterial strains

Sharif¹

2021

PAB

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Microbial resistance to classical antibiotics and have raised serious concern in the treatment of infectious diseases. Recently, many studies have been directed towards finding promising solutions to overcome these problems. Phytochemicals have exerted potential antibacterial activities against sensitive and resistant pathogens via different mechanisms of action. Parthenium hysterophorus is a yearly and local herb used for antibacterial, antifungal, antiviral, anti-parasitic and anthelminthic properties. The present study was conducted to find out the antibacterial potential of Parthenium hysterophorus. Fresh and dry samples of leaves, stem and flowers in ethanol, methanol and acetone extracts were tested against bacterial strains through agar well diffusion assay. Variable results of antimicrobial activity against Klebsiella pneumoniae, Salmonella paratyphi A, Pseudomonas aeruginosa, Proteus mirabilis and Escherichia coli were obtained. Fresh flower, fresh leaves and fresh stem extracts with ethanol, methanol and acetone of P. hysterophorus showed no specific effect on P. mirabilus. Maximum effect was observed both in case of fresh as well as dry plant extracts on E. coli and P. aeruginosa. The findings provide support for the use of Parthenium hysterophorus in producing new bioactivity compounds having antimicrobial activity.

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Parthenium Hysterophorus. L. (Asteraceae) : A Boon or Curse? (A Review)

Cited by 12 publications

References 50 publications

Phytochemical Analysis and In Vitro and In Vivo Pharmacological Evaluation of Parthenium hysterophorus Linn

Phytochemical Analysis and In Vitro and In Vivo Pharmacological Evaluation of Parthenium hysterophorus Linn

Parthenium hysterophorus Being Boon and Bane for Human Beings: A Review

Antimicrobial activity of Parthenium hysterophorus against five bacterial strains

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