Part II: nitroalkenes in the synthesis of heterocyclic compounds

Visible Light‐Induced, Metal‐Free Denitrative [3+2] Cycloaddition for Trisubstituted Pyrrole Synthesis

“…[12] Nitroalkenesa re versatile building blocks for severalt arget scaffolds including various carbocycles and hetrocycles. [13] The strong electron withdrawing nature of the nitro group makes them highlye lectron deficient alkenes, as uitable substrate for numerous organic reactions such as Michael reaction, Mannich reaction, Baylis-Hillman reaction, Rauhut-Currier reaction, cycloadditions and metal-catalyzed coupling reactions. [14] Recently,n itroalkenes have been exploited as the source of alkenyl functioni nv isible light mediated denitrative arylation, [15] trifluoromethylation, [16] carboxylation [17] anda lkylation reactions.…”

Synthesis and characterization of amino glucose-functionalized silica-coated NiFe2O4 nanoparticles: a heterogeneous, new and magnetically separable catalyst for the solvent-free synthesis of pyrano[3,2-c]chromen-5(4H)-ones

“…They offer a model for target-and diversity-oriented synthesis. [16][17][18][19][20] Transition-metal nanoparticles are materials: containing a few tens to several thousand metal atoms, which are stabilized by ligands, polymers or dendrimers as protecting agents for their surfaces. They are heterogeneous catalysis that benets from easy removal of catalyst materials and possible use at high temperatures, suffered for a long time from lack of selectivity and understanding of the mechanistic aspects that are indispensable in parameter improvements.…”

Ultrasound Assisted 1,4-diazabicyclo[2.2.2] Octaniumdiacetate Multicomponent Synthesis of Benzodiazepines: A Novel, Highly Efficient and Green Protocol

“…[16][17][18] Multicomponent reactions (MCRs) are efficient tools in modern synthetic organic chemistry because they are fast, simple, offer high-atomic efficiency, are environ-mentally friendly and save time and energy. [19][20][21][22][23] On the other hand, ionic liquids are suitable compounds because they are non-flammable, non-volatile, soluble, exhibit polarity and are highly thermal and chemically stable. 24 MCRs combined with ionic liquid can assist in the synthesis of the benzodiazepines to reduce the cost of starting materials and decrease the generation of undesirable by-products.…”