Paroxysmal Tachycardia with Episodic Unconsciousness

Electrical heart disease: Genetic and molecular basis of cardiac arrhythmias in normal structural hearts

“…This condition is the latest of the purely electrical conditions of the heart to have a proven genetic basis, inherited as an autosomal dominant (59,60) or recessive (61) genetic disease. The clinical phenotype of bidirectional or polymorphic ventricular tachycardia occurring with physical or emotional stress in patients with structurally normal hearts and normal resting ECGs was first described in isolated case studies in the 1960s and 1970s (62)(63)(64). In 1978, Coumel et al (65) described a series of young patients presenting with catecholamine-induced polymorphic ventricular arrhythmias.…”

Exercise-induced ventricular tachycardia

“…Ventricular tachycardia has been found in children and young adults with no detectable structural heart disease [2,4,6,7,9,10,14,15,[17][18][19]21,25,27,28,31,34,36] . The prognosis has varied, from benign to malignant .…”

Guidelines for Risks and Prevention of Sudden Cardiac Death (JCS 2010) - Digest Version -

“…[124][125][126][127] CPVT is not associated with organic heart diseases, and there is no sex difference in incidence. In patients with CPVT, exercise and intravenous isoproterenol induce a gradual increase in PVC, which further lead to polymorphic or bidirectional VT, very fast polymorphic VT (350 to 400/min), and finally to VF.…”