Paroxysmal atrial fibrillation following marijuana intoxication: a two-case report of possible association

Kosior, Dariusz A.; Filipiak‬, Krzysztof J.; Stolarz, Przemysław; Opolski, Grzegorz

doi:10.1016/s0167-5273(00)00459-9

Cited by 81 publications

(51 citation statements)

References 5 publications

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“…Myocardial infarction following cannabis use and Viagra (Pfizer Canada Inc) consumption has been reported (42). The increase in heart rate following cannabis use may play a role by increasing myocardial oxygen demand, but other factors, such as plaque rupture and arrhythmias, may also have an effect (43)(44)(45).…”

Section: Acute Effectsmentioning

confidence: 99%

Safety Issues Concerning the Medical Use of Cannabis and Cannabinoids

Ware

Tawfik

2005

Pain Research and Management

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Safety issues are a major barrier to the use of cannabis and cannabinoid medications for clinical purposes. Information on the safety of herbal cannabis may be derived from studies of recreational cannabis use, but cannabis exposure and effects may differ widely between medical and recreational cannabis users. Standardized, quality-controlled cannabinoid products are available in Canada, and safety profiles of approved medications are available through the Canadian formulary. In the present article, the evidence behind major safety issues related to cannabis use is summarized, with the aim of promoting informed dialogue between physicians and patients in whom cannabinoid therapy is being considered. Caution is advised in interpreting these data, because clinical experience with cannabinoid use is in the early stages. There is a need for long-term safety monitoring of patients using cannabinoids for a wide variety of conditions, to further guide therapeutic decisions and public policy.

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Section: Acute Effectsmentioning

confidence: 99%

Safety Issues Concerning the Medical Use of Cannabis and Cannabinoids

Ware

Tawfik

2005

Pain Research and Management

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“…Other serious complications associated with SC use include cardiac arrhythmias, myocardial infarction, ST segment abnormalities on electrocardiogram, and seizures. 16,20,26,28,[32][33][34][35][36][37] The cardiac arrhythmias may be attributed to the β-agonist activity of clenbuterol. 16,24 Case reports also suggest that tachyphylaxis can develop after only a few doses, leading to an increased risk of overdose with continued use.…”

Section: Synthetic Cannabinoidsmentioning

confidence: 99%

Emergence of New Classes of Recreational Drugs—Synthetic Cannabinoids and Cathinones

2014

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Designer drugs represent an increasingly popular form of recreational substance abuse, especially amongst young adults. The two classes of designer drugs that have recently risen to prominence are the synthetic cannabinoids and synthetic cathinones. These substances are not detected by conventional drug screening methods and can often be associated with serious health consequences, including seizures, renal failure and death. Thus, clinicians should be familiar with the signs, symptoms, and toxicities associated with the use of these substances, and maintain a high level of suspicion for synthetic drugs as an alternative means of "getting high." We present a case of a 20-year-old college student who presented to the emergency department with altered mental status and severe agitation who later admitted to using bath salts. The goal of this article is to raise awareness about these new designer drugs, their clinical presentation, and management of their intoxication.

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“…Petronis et al [27] using age-matched controls in the survey data from the National Institute of Mental Health Epidemiologic Catchment Area Program reported that marijuana was associated with an age-and race-adjusted relative risk of 1.5 (95% CI = 1.1-2.1) for palpitations, while daily use of this drug increased the relative risk to 2.2 (95% CI = 1.6-3.3). The occurrence of atrial fibrillation has also been linked to use of marijuana [27][28][29]. One case report described sudden occurrence of atrial fibrillation in a 14-yearold boy immediately after smoking marijuana [28].…”

Section: Tachyarrhythmiasmentioning

confidence: 99%