Parosmia

Zilstorff, K.

doi:10.1017/s0022215100066457

Cited by 28 publications

(15 citation statements)

References 5 publications

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“…While binasal cocaine installation inhibited phantosmia in BPAS, as observed by others [442,443], this inhibition was only temporary. In CUP there was usually a post anesthesia inhibitory period along with the production of hyposmia.…”

Section: Discussionsupporting

confidence: 71%

Olfactory Hallucinations without Clinical Motor Activity: A Comparison of Unirhinal with Birhinal Phantosmia

2013

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Olfactory hallucinations without subsequent myoclonic activity have not been well characterized or understood. Herein we describe, in a retrospective study, two major forms of olfactory hallucinations labeled phantosmias: one, unirhinal, the other, birhinal. To describe these disorders we performed several procedures to elucidate similarities and differences between these processes. From 1272, patients evaluated for taste and smell dysfunction at The Taste and Smell Clinic, Washington, DC with clinical history, neurological and otolaryngological examinations, evaluations of taste and smell function, EEG and neuroradiological studies 40 exhibited cyclic unirhinal phantosmia (CUP) usually without hyposmia whereas 88 exhibited non-cyclic birhinal phantosmia with associated symptomology (BPAS) with hyposmia. Patients with CUP developed phantosmia spontaneously or after laughing, coughing or shouting initially with spontaneous inhibition and subsequently with Valsalva maneuvers, sleep or nasal water inhalation; they had frequent EEG changes usually ipsilateral sharp waves. Patients with BPAS developed phantosmia secondary to several clinical events usually after hyposmia onset with few EEG changes; their phantosmia could not be initiated or inhibited by any physiological maneuver. CUP is uncommonly encountered and represents a newly defined clinical syndrome. BPAS is commonly encountered, has been observed previously but has not been clearly defined. Mechanisms responsible for phantosmia in each group were related to decreased gamma-aminobutyric acid (GABA) activity in specific brain regions. Treatment which activated brain GABA inhibited phantosmia in both groups.

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Section: Discussionsupporting

confidence: 71%

Olfactory Hallucinations without Clinical Motor Activity: A Comparison of Unirhinal with Birhinal Phantosmia

2013

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“…19 Several neurologic agents have been tried for smell disorders, including sedatives, antidepressants, and antiepileptic drugs without benefit. 19,49 Maximal medical therapy for CRS includes topical and/or systemic corticosteroids. 20 Despite the importance of steroids in managing CRS postoperatively, their role in improving olfaction is unclear.…”

Section: Postoperative Considerations For Smell Lossmentioning

confidence: 99%

Olfaction in Endoscopic Sinus and Skull Base Surgery

Thompson

Kern

Conley

2015

Otolaryngologic Clinics of North America

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“…Phantosmia has been found to occur in 6% of community dwelling adults and up to 12% in a tertiary otolaryngology clinic . The majority had concomitant anosmia/hyposmia, and most phantosmias presented with no history of upper respiratory tract infection, head trauma or aging (idiopathic) . A typical history begins in a woman between the ages of 15–30 years old, who notices odor perception that is not appreciated by others.…”

Section: Case Historiesmentioning

confidence: 99%

“…Lastly, there is a group of patients with olfactory hallucination without clinical motor activity and no clear cause found . The phantosmia tends to be spontaneous, worse after coughing, laughing, and shouting.…”

Section: Case Historiesmentioning

confidence: 99%

“…Analgesics were not found to be helpful for phantosmia in children, though sleep helped to minimize or terminate it . Administration of topical nasal saline drops as needed in the head down and forward (Mecca) position, oxymetazoline HCl, and topical cocaine HCl blocks air flow and anesthetizes the olfactory cleft with improvement in symptoms . However, olfactory cocainization was shown to be an ineffective long‐term solution for phantosmia with resolution and improvement being transient and unsustained and retreatment necessary in 2 weeks to 4 months …”

Section: Case Historiesmentioning

confidence: 99%

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