Parkinsonism and Potential of Mucuna Beans

Abstract

Parkinson’s is a neurodegenerative disease, which is common all over the world. Various aspect like damages of reactive oxygen species, excitotoxicity, mitochondrial dysfunction, and inflammation-facilitated cell damages are included in the etiology of disease. Good-balanced nutrition is an important part involved in the body health maintenance and reduction in the risk of chronic diseases. Genus Mucuna falls under family Fabaceae, containing high contents of L-DOPA (commonly used as an anti-Parkinson drug). Plant-based medicines are the superfluous source of polyphenols, flavonoids, carotenoids, antioxidants (ROS and RNS), terpenoids, isoflavonoids, and other biologically active phytochemicals. All these molecules have health beneficial effects with superlative pharmaceutical values. The existing chapter summaries to determine the influence of different nutritional, anti-nutritional, and medicinal potential of the Mucuna species present in India and its significance in the management of Parkinson’s disease (Shaking Palsy) as well as other medicinal values. It also covers various treatment models used in studying the Parkinson’s disease like Drosophila melanogaster, zebrafish, mice, rat, and humans. This chapter also focuses light on the neurosurgical treatments used in the treatment of Parkinson’s disease. This study concluded that the use of Mucuna seeds for the treatment of Parkinson’s disease is the best choice besides chemical drugs and other therapies.

The perspectives of traditional and modern medicine on the nature of hot and cold foods

“…A balanced diet that contains adequate protein, vitamins and minerals, probiotics, and a moderate amount of saturated fat can help the body to produce dopamine. People with dopamine deficiency diseases, such as Parkinson's disease, increase their dopamine levels by eating dopamine-rich food sources, such as fava beans or velvet beans, also www.journals.viamedica.pl/medical_research_journal known as Mucuna pruriens, duck, eggs, and certain fresh cheeses (cottage cheese) [52].…”