Parkinson’s Disease: New Insights

A, Ivana Scovassi

doi:10.4172/2167-0501.1000e146

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2015

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“…The evidence that mitochondria and ROS as the main neurodegeneration players have caused antioxidant remedies opens new perspectives of research and therapy as possible preventive and therapeutic approaches for PD [11].…”

Section: Introductionmentioning

confidence: 99%

Oxidative stress and Parkinson's disease: New hopes in treatment with herbal antioxidants

Sarrafchi¹,

Bahmani²,

Shirzad³

et al. 2015

CPD

152

101

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Parkinson's disease (PD) is a neurodegenerative disorder due to dopamine deficit in substatia nigra. PD is mainly a sporadic disease with unestablished etiology. However, exposure to environmental toxins, head trauma, inflammation, and free radicals are potential reasons. Recently, the role of oxidative stress in neurological abnormalities, including PD, has been particularly addressed. Antioxidant remedies, particularly herbal antioxidants, have revealed new perspectives of research and therapy as possible preventive and therapeutic approaches for PD. In this paper, we reviewed the recently published papers on the effects of herbal medicines on PD alongside the pathogenesis of PD with regard to oxidative stress.

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Section: Introductionmentioning

confidence: 99%