Parkinson Hastalığı ve Atipik Parkinson Sendromlarının Ayırıcı Tanısı

Abstract

Clinical diagnosis of Parkinson's disease demonstrates classical presentation of symptoms that are often misdiagnosed as Parkinsonian syndromes predominately in the initial stages of the disease. Innovative clinical trials for the differential diagnosis between the two overlapping illnesses incorporate neuroimaging, pharmalogical medications, deep brain stimulation and cerebrospinal biomarkers. At present, therapeutic options are applicable in reducing symptomalogy while delaying the onset of the disease. In this article, Parkinson's disease and atypical parkinsonian syndromes are comprehensively discussed in relations to symptoms, etiology, diagnosis and treatment.