Parietal Cephaloceles: Radiographic and Magnetic Resonance Imaging Evaluation

Jt, Curnes; Wj, Oakes

doi:10.1159/000120366

Cited by 21 publications

(14 citation statements)

References 6 publications

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“…The association with these malformations is not unexpected, due to various pathophysiological events leading to cephalocele. The previously reported CNS anomalies include: dysgenesis of the corpus callosum, formation of interhemispheric fissure, split superior sagittal sinus, absence of falx cerebri and dysgenesis of the tentorium [17,18,19]. Mahapatra and Agrawal [20] reported that corpus callosum agenesis is seen in 7% of children with anterior encephaloceles in a series of 103 cases aged over 32 years.…”

Section: Discussionmentioning

confidence: 99%

Cephalocele: Report of 55 Cases over 8 Years

et al. 2009

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Objective: Cephalocele is a central nervous system (CNS) birth defect. Various CNS and extra-CNS anomalies, as well as prognostic factors have been reported with cephalocele. The aim of this study was to discuss prognostic factors and current possible theories explaining associated anomalies seen in a series of 55 patients with cephalocele. Methods: A retrospective study was performed using the records of 55 children with cephalocele at the Children’s Hospital Medical Center in Tehran, Iran, from October 2000 through October 2008. Patients’ sex, age at the operation time, characteristics of the lesion including location, size, cerebrospinal fluid leakage, radiological assessments and intraoperative findings (sac contents), intracranial and extracranial associated anomalies, and the last situation of the children were reviewed. Conclusion: A genetic role can be proposed while a female predominance is seen in our results as well as in other reports. CNS and extra-CNS anomalies, as well as several genetic syndromes are not explicable as a causal consequence of cephalocele and the probability of a mere coincidence cannot be ruled out; therefore, we propose that the combination of these anomalies is rather a low-frequency association. Ventriculomegaly was the only poor prognostic determinant in our study, which can compel more severe neuroradiologic studies in such patients as a reasonable prognostic evaluation.

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Section: Discussionmentioning

confidence: 99%

Cephalocele: Report of 55 Cases over 8 Years

et al. 2009

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“…Less common sites include the frontal region where the encephalocele may protrude into the nasal cavity. Least common lesion sites include the temporal and parietal region (46). The neural tissue in an encephalocele usually connects to the underlying central nervous system through a narrow neck of tissue.…”

mentioning

confidence: 99%

Folate, Homocysteine and Neural Tube Defects: An Overview

Nm¹,

Fj³

et al. 2001

Exp Biol Med (Maywood)

252

149

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Folate administration substantially reduces the risk on neural tube defects (NTD). The interest for studying a disturbed homocysteine (Hcy) metabolism in relation to NTD was raised by the observation of elevated blood Hcy levels in mothers of a NTD child. This observation resulted in the examination of enzymes involved in the folate-dependent Hcy metabolism. Thus far, this has led to the identification of the first and likely a second genetic risk factor for NTD. The C677T and A1298C mutations in the methylenetetrahydrofolate reductase (MTHFR) gene are associated with an increased risk of NTD and cause elevated Hcy concentrations. These levels can be normalized by additional folate intake. Thus, a dysfunctional MTHFR partly explains the observed elevated Hcy levels in women with NTD pregnancies and also, in part, the protective effect of folate on NTD. Although the MTHFR polymorphisms are only moderate risk factors, population-wide they may account for an important part of the observed NTD prevalence.

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“…11,13,22 Interestingly, venous involvement in patients with parietal encephaloceles has been reported occasionally. 5,7,15,17,19 In this article we describe an unusual case of congenital extracranial teratoma coexisting with an IPE, in which a persistent primitive falcine vein and a bifid sagittal sinus were demonstrated on MR venography. 5,7,15,17,19 In this article we describe an unusual case of congenital extracranial teratoma coexisting with an IPE, in which a persistent primitive falcine vein and a bifid sagittal sinus were demonstrated on MR venography.…”

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confidence: 96%

Mature teratoma associated with an interparietal encephalocele

Turğut¹,

Ibrahim²

2007

Journal of Neurosurgery: Pediatrics

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Teratomas and encephaloceles are both uncommon congenital malformations that originate near the midline in the head and neck. An encephalocele is an extracranial extension of intracranial structures through a defect in the skull, whereas a teratoma consists of tissue from all three embryonic germ layers and is a true congenital tumor. In the present study the authors describe the first reported case of a mature teratoma associated with an interparietal encephalocele presenting as a large midline subcutaneous mass in a newborn child. The appearance of these two pathological entities together suggests a common origin. The embryological significance of this finding is discussed, and the pertinent literature is reviewed.

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Parietal Cephaloceles: Radiographic and Magnetic Resonance Imaging Evaluation

Cited by 21 publications

References 6 publications

Cephalocele: Report of 55 Cases over 8 Years

Cephalocele: Report of 55 Cases over 8 Years

Folate, Homocysteine and Neural Tube Defects: An Overview

Mature teratoma associated with an interparietal encephalocele

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