Parents Matter: Intergenerational Influences of Diabetes Mellitus on Glycemic Control and Morbidity in Older Type 2 Diabetic Males

Perlmuter, Lawrence C.; Singh, Sant P.; Gabhart, Julia M.; Pungan, Ramona; Siedlarz, Monika

doi:10.1080/03610730701876961

Cited by 5 publications

(3 citation statements)

References 27 publications

(37 reference statements)

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“…Beside age and gender [13], multiple other risk factors and co-morbidities are associated with either one or both diseases. These include socioeconomic status [14], past history of (h/o) depression [15], family h/o diabetes [16], h/o gestational diabetes [17], family type [18], Body Mass Index (BMI) [19-21], h/o smoking [22], h/o high cholesterol [23,24] and h/o high blood pressure (BP) [25]. …”

Section: Introductionmentioning

confidence: 99%

Association of depression with newly diagnosed type 2 diabetes among adults aged between 25 to 60 years in Karachi, Pakistan

Perveen

Otho²,

Siddiqi

et al. 2010

Diabetol Metab Syndr

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BackgroundThe combination of depression with type 2 diabetes is a public health problem. If diabetes is managed in its initial phase, the morbidity and mortality due to this combination may be prevented at an early stage. Therefore, we aimed to determine the association of depression with newly diagnosed type 2 diabetes among adults aged between 25 to 60 years in Karachi, Pakistan.MethodsFrom July 2006 to September 2007, a matched case control study (n = 592) was conducted in Civil Hospital, Karachi. Incident cases of type 2 diabetes (n = 296) diagnosed within one month were recruited from diabetic Out Patient Department (OPD) of Civil Hospital, Karachi. They were matched on age and sex with controls (n = 296), who were attendants sitting in the medical out patient department of the same hospital, recruited on the basis of absence of classical symptoms of polyuria and polydispia along with random blood glucose level of <200 mg/dl measured by a glucometer. Depression was identified by the Siddiqui Shah Depression Scale. Conditional logistic regression was applied to examine the association of depression and other independent variables with newly diagnosed type 2 diabetes at 95% C.I. and P < 0.05.ResultsThe study comprised of 592 subjects with 432(73%) males and 160(27%) females. Depression was significantly associated with newly diagnosed type 2 diabetes having mild level (mOR: 3.86; 95%CI: 2.22,6.71) and moderate to severe level (mOR: 3.41; 95%CI: 2.07,5.61). History of (h/o) gestational diabetes (mOR: 2.83; 95%CI: 1.05,7.64), family h/o diabetes (mOR: 1.59; 95%CI: 1.04,2.43), nuclear family (mOR: 1.75; 95%CI: 1.14,2.69), BMI (mOR: 1.62; 95%CI: 1.01,2.60 for obese and mOR: 2.12; 95%CI: 1.19,3.79 for overweight vs healthy to underweight) were also significantly associated with outcome, adjusting for age, sex, marital status, h/o smoking and h/o high BP.ConclusionsDiabetics should be screened simultaneously for depression and concomitant preventive strategies for gestational diabetes, nuclear family and high BMI should also be used to prevent mortality/morbidity among patients between 25 to 60 years of age.

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Section: Introductionmentioning

confidence: 99%

Association of depression with newly diagnosed type 2 diabetes among adults aged between 25 to 60 years in Karachi, Pakistan

Perveen

Otho²,

Siddiqi

et al. 2010

Diabetol Metab Syndr

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“…In a cross-sectional study, the effects of disease duration of type 2 diabetes mellitus (DM) were examined along with parent history of DM on disease-related outcome variables (Perlmuter, Singh, Gabhart, Pungan, & Siedlarz, 2008). Specifically, the moderating role of parent history of DM on outcome variables was examined.…”

Section: United States Of Americamentioning

confidence: 99%

Relational Competence Theory

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Cusinato

Maino

et al. 2010

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“…La diabetes es también otro factor de riesgo causal. Varios estudios realizados en este campo (Perlmuer, Singh P., Gabhart J., Pungan R. y Siedlarz M., 2008) (Raz, 2000).…”

Section: Cambios Molecularesunclassified

Estudio normativo de la Dementia Rating Scale-2 en una muestra poblacional española mayor de 60 años

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Parents Matter: Intergenerational Influences of Diabetes Mellitus on Glycemic Control and Morbidity in Older Type 2 Diabetic Males

Cited by 5 publications

References 27 publications

Association of depression with newly diagnosed type 2 diabetes among adults aged between 25 to 60 years in Karachi, Pakistan

Association of depression with newly diagnosed type 2 diabetes among adults aged between 25 to 60 years in Karachi, Pakistan

Relational Competence Theory

Estudio normativo de la Dementia Rating Scale-2 en una muestra poblacional española mayor de 60 años

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