Parenterally Administered Moderate Sedation and Paracervical Block Versus General Anesthesia for Hysteroscopic Polypectomy: A Pilot Study Comparing Postoperative Outcomes

Centini, Gabriele; Calonaci, Andrea; Lazzeri, Lucia; Tosti, Claudia; Palomba, Caterina; Puzzutiello, Rosa; Luisi, Stefano; Zupi, Errico

doi:10.1016/j.jmig.2014.09.008

Cited by 13 publications

(9 citation statements)

References 21 publications

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“…In the study, the tool of BPI (Brief Pain Inventory) was used because the pain score based on VAS scale was reported less than 3 in all patients. Finally, they concluded that women who had a combination of two methods of PB and IVS felt significantly less pain on daily activities [18]. In addition to differences in the types of interventions, it seems that the differences between the findings of the study and the present study were use of various pain assessment tools.…”

Section: Discussionmentioning

confidence: 63%

“…Several studies have suggested that we do not need any anesthesia during diagnostic hysteroscopic procedures [11–17]. In a study conducted by Centini et al, it has been concluded that moderate sedation together with a PB will reduce pain perception and the operative time will decrease [18]. Cooper et al reported outpatient polypectomy which uses local anesthesia is more safe and time and cost effective, although the inpatient procedure under GA was more successful noting that patients undergoing outpatient surgery were twice more likely to undergo another surgery after two years [19].…”

Section: Introductionmentioning

confidence: 99%

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Evaluation of Paracervical Block and IV Sedation for Pain Management during Hysteroscopic Polypectomy: A Randomized Clinical Trial

Asgari

Razavi

Hosseini

et al. 2017

Pain Research and Management

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Background The aim of this study was to compare the effectiveness of paracervical block (PB) and IV sedation (IVS) on women's pain perception during operative hysteroscopy. Methods A total of 84 patients with uterine polyps were randomized to either PB or IV sedation or general anesthesia (GA) as control group. In PB group, the patients received oral diazepam 10 mg and 100 mg diclofenac Na suppository 60 min before surgery and 10 cc of 2% buffered lidocaine was injected at cervix. Conscious sedation was performed with the IV administration of 2-3 mg/kg/h propofol 1% and midazolam 0.02 mg/kg and fentanyl (1-2 μg/kg) with o2 4-5 lit/min via face mask. Results There were no significant differences between groups on VAS score at 3 hours after operation (PB: 1.22 ± (1.31), IVS: 1.10 ± (1.68), GA: 1.29 ± (2.03), P = 0.671) and during recovery (PB: 0.85 ± (1.06), IVS: 0.68 ± (1.33), GA: 1.21 ± (2.04), P = 0.458). There was no difference between PB (3.33 ± (2.81)) and IVS (2.31 ± (2.63)) groups at hysteroscopy (P = 0.182). Patients undergoing IVS reported lower VAS score than PB group at dilation and curettage, although the difference was not statistically significant (PB: 2.59 ± (1.78), IVS: 1.72 ± (2.34), P = 0.051). Moreover, patients undergoing IVS obtained lower VAS score than PB group at polypectomy, while the difference was not statistically significant (PB: 1.81 ± (1.52), IVS: 1.10 ± (1.32), P = 0.073). Conclusion The finding of the present study revealed that IVS and PB showed the same effect in reducing pain during and after gynecological surgical procedures. The study was registered in Iranian Registry of Clinical Trial with the number IRCT2016031426855N3, on April 28, 2016.

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Section: Discussionmentioning

confidence: 63%

Section: Introductionmentioning

confidence: 99%

Evaluation of Paracervical Block and IV Sedation for Pain Management during Hysteroscopic Polypectomy: A Randomized Clinical Trial

Asgari

Razavi

Hosseini

et al. 2017

Pain Research and Management

View full text Add to dashboard Cite

show abstract

“…However, the pain ratings were not fully comparable between the two groups due to the great variety in time of recording after the operation in the ORS group. Centini et al compared parenterally administered moderate sedation and paracervical block versus general anaesthesia during day-case hysteroscopy for polypectomy [11]. Analysis of patients' discomfort showed a higher frequency of movements and moans in the paracervical block and sedation group and more often use of analgesic or antiemetic drugs after surgery in the general anaesthesia group, although both findings were not statistically significant.…”

Section: Discussionmentioning

confidence: 99%

Therapeutic hysteroscopy in an outpatient office-based setting compared to conventional inpatient treatment: superior? a cohort study

et al. 2016

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“…IV infusions of 1-4 mg/min causes a serum range of 1-5 mg/L. IM dose would be for 4-5 mg/Kg which is about 20cc or 200 mg causes the same level [1][2][3][4][5][6][7][8][9][10].…”

Section: Dosagementioning

confidence: 99%

Local Intrauterine Anesthesia

2019

JGRM

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The first local anesthetic to be discovered was cocaine an alkaloid in large amount (0.6 to 1.8%) on the leaves of Erythroxylon coca a shrub growing in the Andes Mountains. Vast quantities were consumed orally and annually. The plant ash when chewed releases the plant alkaloid and absorbed across the mouth mucous membrane. In 1880 Niemann noted that the tongue was numb with no sensation upon chewing this substance. It is well known that Lidocaine was absorbed across the mucous membrane.

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Parenterally Administered Moderate Sedation and Paracervical Block Versus General Anesthesia for Hysteroscopic Polypectomy: A Pilot Study Comparing Postoperative Outcomes

Cited by 13 publications

References 21 publications

Evaluation of Paracervical Block and IV Sedation for Pain Management during Hysteroscopic Polypectomy: A Randomized Clinical Trial

Evaluation of Paracervical Block and IV Sedation for Pain Management during Hysteroscopic Polypectomy: A Randomized Clinical Trial

Therapeutic hysteroscopy in an outpatient office-based setting compared to conventional inpatient treatment: superior? a cohort study

Local Intrauterine Anesthesia

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