Parenteral Nutrition in Low Birth Weight Babies

Shaw, J.

doi:10.1007/978-94-010-2363-4_16

Cited by 5 publications

(9 citation statements)

References 12 publications

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“…Despite these advances, there is still a poor understanding of fetal bone development, but it is known that a mechanism to maintain rapid bone development is established in late pregnancy, in which large amounts of calcium and phosphorus from the mother are deposited in fetal bone, while bone resorption is inhibited (Shaw 1973;Ziegler et al 1976;Itani and Tsang 2006;Mitchell and Jüppner 2010).…”

Section: Discussionmentioning

confidence: 99%

“…Minerals required for fetal bone development are mostly transferred to the fetus in late pregnancy; however, many aspects of this process remain unclear (Shaw 1973;Ziegler et al 1976). Various biochemical markers of bone development have been identified in cord blood and blood of neonates (Itani and Tsang 2006); and in Japanese adults, bone resorption markers in urine are commonly used to assess bone metabolism.…”

Section: Introductionmentioning

confidence: 99%

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Fetal Bone Formation Is Decreased from Middle Pregnancy to Birth

Nitta

Suzumura

Arisaka

et al. 2016

Tohoku J. Exp. Med.

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Fetal bone development is a complex process that is regulated and maintained by minerals, hormones, and growth factors delivered from the mother via the placenta. Various biochemical markers of fetal bone development have been identified. However, many aspects of this process remain unclear. The aim of the study was to measure the activities of serum tartrate-resistant acid phosphatase type 5b (TRACP 5b) as a bone resorption marker and bone alkaline phosphatase (BAP) as a bone formation marker in preterm and term neonates, and to investigate fetal bone development in middle and late pregnancy. The study included 111 neonates (87 preterm and 24 term) born at Dokkyo Medical University Hospital. Neonates with illnesses and maternal diseases were excluded. Serum samples were collected within 3 hours after birth and stored at −80°C. Univariate and multivariate linear regression analyses were performed. The 111 neonates (median birth weight, 1,510 g) were born at a median of 31.3 weeks of gestation, and had TRACP 5b and BAP activities of 10.9 ± 4.0 U/L and 127.5 ± 49.2 U/L, respectively. TRACP 5b activity showed a tendency to be higher in term neonates, while BAP activity tended to be lower in term neonates. Importantly, TRACP 5b activity was positively correlated with gestational age and birth weight, and BAP activity was negatively correlated with gestational age, rate of born small-for-gestational-age neonates, and birth weight. These results suggest that bone formation during fetal growth is gradually decreased from middle pregnancy to birth, whereas bone resorption is gradually increased.Keywords: bone alkaline phosphatase; fetal bone development; preterm neonate; tartrate-resistant acid phosphatase type 5b; term neonate Tohoku J.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Fetal Bone Formation Is Decreased from Middle Pregnancy to Birth

Nitta

Suzumura

Arisaka

et al. 2016

Tohoku J. Exp. Med.

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“…The use of amino acid solutions allows growth to continue, provided enough calories are being supplied. The amount of nitrogen accumulated by the fetus during the third trimester is known from previous investigations (2,3,4). However, the exact amount of amino acid nitrogen, and the optimal composition of an amino acid solution to be parenterally administered has not yet been established.…”

mentioning

confidence: 99%

Amino Acids in Parenteral Nutrition of Preterm Infants

et al. 1983

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Parenteral feeding of preterm infants has been accepted as an alternative form of nutrition in those infants unable to accept oral feeding. The amount of amino acid nitrogen and the composition of the amino acid solution to be used, however, have not yet been defined. The amino acid intake and the plasma amino acid concentration of three groups of preterm infants were compared. Twenty-three infants were fed parenterally. Of these, 16 were studied during the first week of life (group I) and 7 during the second week (group II). A control group of 9 infants fed with oral formula was also studied in the second week (group III). In general, plasma amino acid concentrations in the parenterally fed groups were higher than in the orally fed group, in spite of a lower intake. Comparison of the amino acid intake of groups I and II relative to group III, with the plasma amino acid concentrations of groups I and II relative to group III, revealed a rather constant ratio with the exception of tyrosine and aspartic acid, where higher values were found. It is concluded that further increase in the amino acid nitrogen in parenteral feeding of preterm infants requires a more adapted preparation.

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“…Περιέχουν ακόμη σέ επικίνδυνα υψηλά ποσοστά τα αμινοξέα μεθειονίνη και γλυκίνη καθώς και υψηλά ποσά αμ μωνίας (1000 -3600 mg %) 10 , 41 που αποδίδουν μεγάλα ποσά ουρίας. Έκ τος αύτοϋ έχουν περιγραφεί και έγκεφαλοπάθειες άπα ύπεραμμωνιαιμία κατά τή χορήγηση τους 38 . Έπί πλέον τά διαλύματα αυτά έχουν υψηλό τίτλο οξύτητας 42 .…”

Section: πρωτεΐνεςunclassified

“…Έπί πλέον τά διαλύματα αυτά έχουν υψηλό τίτλο οξύτητας 42 . Τέλος, έχουν παρατηρηθεί αντιδράσεις υπερευαισθησίας, οί όποιες αποδόθηκαν στην ύπαρξη των διπεπτιδίων, σέ άτομα πού εμφάνι ζαν κάποια αλλεργία στην πρωτεΐνη 15 , 38 .…”

Section: πρωτεΐνεςunclassified

Παρεντερικη Διατροφη Στα Πολυ Μικρου Βαρους Προωρα Νεογνα

Χατζηδημητριου¹

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Parenteral Nutrition in Low Birth Weight Babies

Cited by 5 publications

References 12 publications

Fetal Bone Formation Is Decreased from Middle Pregnancy to Birth

Fetal Bone Formation Is Decreased from Middle Pregnancy to Birth

Amino Acids in Parenteral Nutrition of Preterm Infants

Παρεντερικη Διατροφη Στα Πολυ Μικρου Βαρους Προωρα Νεογνα

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