Parental Exposure to Morphine Before Conception Decreases Morphine and Cocaine‐Induced Locomotor Sensitization in Male Offspring
Amirhossein Heidari,
Arman Hajikarim‐Hamedani,
Saereh Hosseindoost
et al.
Abstract:Repeated exposure to abused drugs leads to reorganizing synaptic connections in the brain, playing a pivotal role in the relapse process. Additionally, recent research has highlighted the impact of parental drug exposure before gestation on subsequent generations. This study aimed to explore the influence of parental morphine exposure 10 days prior to pregnancy on drug‐induced locomotor sensitization. Adult male and female Wistar rats were categorized into morphine‐exposed and control groups. Ten days after th… Show more
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