Parent psychopathology and offspring mental disorders: Results from the WHO World Mental Health Surveys

McLaughlin, Katie A.; Gadermann, Anne M.; Hwang, Irving; Sampson, Nancy A.; Al‐Hamzawi, Ali; Andrade, Laura Helena; Angermeyer, Matthias C.; Benjet, Corina; Bromet, Evelyn J.; Bruffærts, Ronny; Caldas-de-Almeida, José Miguel; Girolamo, Giovanni de; Graaf, Ron de; Florescu, Silvia; Gureje, Oye; Haro, Josep María; Hinkov, Hristo; Horiguchi, Itsuko; Hu, Chiyi; Karam, Aimée; Kovess–Masféty, Viviane; Lee, Paul; Murphy, Samuel D.; Nizamie, S. Haque; Posada‐Villa, José; Williams, Daniel; Kessler, Ronald C.

doi:10.1192/bjp.bp.111.101253

Cited by 225 publications

(180 citation statements)

References 31 publications

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“…3). Psychiatric disease and thyroid disease may coincide (71), and parental psychiatric disease may also associate with the development of disease in the offspring (72).…”

Section: European Journal Of Endocrinologymentioning

confidence: 99%

MECHANISMS IN ENDOCRINOLOGY: Neurodevelopmental disorders in children born to mothers with thyroid dysfunction: evidence of fetal programming?

Andersen¹,

Carlé²,

Karmisholt³

et al. 2017

European Journal of Endocrinology

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Fetal programming is a long-standing, but still evolving, concept that links exposures during pregnancy to the later development of disease in the offspring. A fetal programming effect has been considered within different endocrine axes and in relation to different maternal endocrine diseases. In this critical review, we describe and discuss the hypothesis of fetal programming by maternal thyroid dysfunction in the context of fetal brain development and neurodevelopmental disorders in the offspring. Thyroid hormones are important regulators of early brain development, and evidence from experimental and observational human studies have demonstrated structural and functional abnormalities in the brain caused by the lack or excess of thyroid hormone during fetal brain development. The hypothesis that such abnormalities introduced during early fetal brain development increase susceptibility for the later onset of neurodevelopmental disorders in the offspring is biologically plausible. However, epidemiological studies on the association between maternal thyroid dysfunction and long-term child outcomes are observational in design, and are challenged by important methodological aspects.

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“…3). Psychiatric disease and thyroid disease may coincide (71), and parental psychiatric disease may also associate with the development of disease in the offspring (72).…”

Section: European Journal Of Endocrinologymentioning

confidence: 99%

MECHANISMS IN ENDOCRINOLOGY: Neurodevelopmental disorders in children born to mothers with thyroid dysfunction: evidence of fetal programming?

Andersen¹,

Carlé²,

Karmisholt³

et al. 2017

European Journal of Endocrinology

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show abstract

“…The areas associated with high burdensome scores (3)(4) by the parents were with regards to; quality and cost of care offered, stress and other negative attributes such as embarrassment associated with providing care, inability to meet other parental obligations and uncertainty about the future. Family therapy, in addition to management of schizophrenia, was instituted in the family.…”

Section: Case Reportmentioning

confidence: 99%

“…2 Parental psychopathology, in addition to low socio economic status and exposure to physical violence, has been reported to be strongly associated with childhood mental health disorders. 3,4 In spite of the magnitude of the problem childhood mental health services are either not available or not accessible in low and middle income countries. 1 In response to this the World Health Organization developed the Mental Health Gap Action Programme (mhGAP) for countries especially with low and middle incomes for scaling up services for mental, neurological and substance use disorders.…”

Section: Introductionmentioning

confidence: 99%

Impact of childhood mental health disorders on the family: A Case report

Eseigbe¹,

Eseigbe²,

Nuhu³

et al. 2013

Nig. J. Paed.

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“…We used MPlus Version 6.11 (Muthén & Muthén, 1998-2012 to determine the number of groups with homogenous trajectories of gambling problems and depressive symptoms, respectively.…”

Section: Separate Trajectories Of Gambling Problems and Depressive Symentioning

confidence: 99%

Co-morbidity Between Gambling Problems and Depressive Symptoms: A Longitudinal Perspective of Risk and Protective Factors

et al. 2015

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Parent psychopathology and offspring mental disorders: Results from the WHO World Mental Health Surveys

Abstract: Parent psychopathology is a robust non-specific predictor associated with a substantial proportion of offspring disorders.

Cited by 225 publications

References 31 publications

MECHANISMS IN ENDOCRINOLOGY: Neurodevelopmental disorders in children born to mothers with thyroid dysfunction: evidence of fetal programming?

MECHANISMS IN ENDOCRINOLOGY: Neurodevelopmental disorders in children born to mothers with thyroid dysfunction: evidence of fetal programming?

Impact of childhood mental health disorders on the family: A Case report

Co-morbidity Between Gambling Problems and Depressive Symptoms: A Longitudinal Perspective of Risk and Protective Factors

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