Parent-mediated early intervention for young children with autism spectrum disorders (ASD)

Abstract

Parent-mediated early intervention for young children with autism spectrum disorders (ASD) (Review)

Cultivating Mind: Mindfulness Interventions for Children with Autism Spectrum Disorder and Problem Behaviours, and Their Mothers

“…This may help explain why individuals with ASD commonly present clinically significant problem behaviours (Bearss et al 2013) at a greater level than those with other types of developmental disorders such as Attention Deficit Hyperactivity Disorder (ADHD) (Goldin et al 2013) and intellectual disability (Estes et al 2009). The complex pattern of impairments, heightened anxiety and stress, and clinically significant problem behaviours together create a pronounced parenting challenge (Bearss et al 2013;Oono et al 2013). …”

Oxytocin Treatment, Circuitry, and Autism: A Critical Review of the Literature Placing Oxytocin Into the Autism Context

“…Despite many promoted treatments in the community, often attached with significant cost, most have little evidence to support use (22,23) and are not specified for a sub-type of autism. Most published therapeutic treatments trials are of small sample size, questionable methodological rigour (24)(25)(26)(27), and, like the diagnosis itself, based only on reports of observed behaviour, as opposed to independent objective markers. Risperidone and ariprazole have shown benefit in reducing hyperactivity and aggressive, self-injurious, and repetitive behaviour (22,28), but are associated with significant negative side effects.…”

“…This work demonstrates that young children with autism show considerable potential for learning and 'plasticity' to change and improve developmental trajectories, although patient variables may moderate response. How such interventions can be delivered in a cost-effective manner to produce sustainable outcomes remains unclear (24,42), particularly in lower resourced communities.…”

Outcomes in systematic reviews of complex interventions never reached “high” GRADE ratings when compared with those of simple interventions

“…The integration of subgroup analysis data in decisions on rating the evidence based on inconsistency was not common in the investigated reviews in either of the groups. This could be partially explained by the fact that, in general, an intention of subgroup analysis for the purposes of explaining the sources of heterogeneity was expressed by most reviews; in most cases, it was not conducted [32,35,36,38,47,50,51,53,57,65,66], or conducted for a very limited number of variables [39,41,45,49,55,60,63,64], mainly due to an insufficient number of studies.…”

“…X X X Bennett[46] X X X X X X Bisson[31] X X X X X Churchill[32] X X X X X Cooney[33] X X X X Coren[47] X X X X X X X X Dangour[48] X X X X X X X X Fellmeth[34] X X X X X X X Fletcher-Watson[35] X X X X X Hunot[36] X X X X James[37] X X X X X Langford[49] X X X X X X X X X Livingstone[38] X X X X X X Martin[39] X X X X X X X Mayo-Wilson[40] X X X X X Oono[41] X X X X X X Parab[42] X X X X X Pega[50] X X X X X X X Petrosino[43] X X X X X Rosendal[44] X X X X Shinohara[45] X X X X Thomson[8] X X X X X X X Turley[51] X X X X X X X Winokur[52] X X X X X X ''Simple'' intervention reviews Brown[53] Cipriani[54] Guaiana[55] …”