1988
DOI: 10.1093/bja/61.6.652
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Paravertebral Block During Cholecystectomy: Effects on Circulatory and Hormonal Responses

Abstract: Surgical trauma induces a hormonal metabolic response which is partly responsible for postoperative catabolism. In this study 12 patients underwent cholecystectomy during isoflurane anaesthesia, six with a paravertebral block (PVB) in addition. Plasma concentrations of glucose, cortisol and adrenaline, and heart rate and arterial pressure were compared between the two groups. The patients with PVB showed a significantly diminished response to noxious stimuli.

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Cited by 66 publications
(25 citation statements)
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“…Somatic paravertebral block provides prolonged duration of action and a high margin of safety. [1][2][3][4][5][6][7][8][9][10][11][12] While the technique has been shown to be effective and safe in children undergoing certain procedures, including thoracotomies and urological surgeries, 1-8 the study of its use is limited in this age group and more specifically in pediatric appendectomies. Somatic paravertebral block has been demonstrated to provide effective analgesia in adults for a variety of procedures, including unilateral thoracic and abdominal surgeries, and to offer pain relief with minimal undesirable effects compared with epidural, intercostal, or intrapleural analgesia.…”
Section: Résumémentioning
confidence: 99%
See 1 more Smart Citation
“…Somatic paravertebral block provides prolonged duration of action and a high margin of safety. [1][2][3][4][5][6][7][8][9][10][11][12] While the technique has been shown to be effective and safe in children undergoing certain procedures, including thoracotomies and urological surgeries, 1-8 the study of its use is limited in this age group and more specifically in pediatric appendectomies. Somatic paravertebral block has been demonstrated to provide effective analgesia in adults for a variety of procedures, including unilateral thoracic and abdominal surgeries, and to offer pain relief with minimal undesirable effects compared with epidural, intercostal, or intrapleural analgesia.…”
Section: Résumémentioning
confidence: 99%
“…Somatic paravertebral block has been demonstrated to provide effective analgesia in adults for a variety of procedures, including unilateral thoracic and abdominal surgeries, and to offer pain relief with minimal undesirable effects compared with epidural, intercostal, or intrapleural analgesia. [8][9][10][11][12] This study compared SPVB with no block and examined postoperative analgesic requirements as the primary endpoint in children undergoing open appendectomy. We hypothesized that SPVB would provide superior and prolonged pain relief and would minimize opioid requirements in the postoperative period.…”
Section: Résumémentioning
confidence: 99%
“…1,2 Multiple-segment paravertebral blocks (PVBs) in inguinal hernia surgeries are reported to provide high-quality intraoperative anesthesia and postoperative analgesia and suppress the stress response to surgical stimuli. 3,4 To increase patient comfort and shorten the time for block performance, we use a 2-segment PVB approach in inguinal hernia surgeries.…”
mentioning
confidence: 99%
“…He also demonstrated the benefit of paravertebral blockade after thoracotomy [3]. Paravertebra1 block reduces the stress response to cholecystectomy [4], provides equally effective post-thoracotomy pain relief with fewer complications than thoracic epidural analgesia [5] and has been used successfully in the care of patients in chronic pain [6]. The method has recently been modified for children with promising results [7,8].…”
mentioning
confidence: 99%