Parathyroid Cyst Presenting as Acute Pancreatitis: Report of a Case

Kim, Miyoung; Chung, Chul; Kim, Jong-Sun; Myung, Dae‐Seong; Cho, Sung-Bum; Park, Chang-Hwan; Kim, Young; Joo, Young‐Eun

doi:10.4068/cmj.2013.49.3.125

Cited by 3 publications

(1 citation statement)

References 9 publications

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“…In agreement with previous studies, cystic parathyroid adenomas in the present cohort were found to be associated with high serum levels of iPTH and calcium [ 5 , 21 ]. Additionally, a higher incidence of hypercalcemic crisis was observed in patients with cystic adenomas than in patients with solid adenomas.…”

Section: Discussionsupporting

confidence: 93%

The Clinical Features of Cystic Parathyroid Adenoma in Chinese Population: A Single-Center Experience

Cui

Xia

et al. 2018

International Journal of Endocrinology

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Objective Cystic parathyroid adenoma is a rare cause of primary hyperparathyroidism, but its preoperative diagnosis and management remain inconclusive. Method We retrospectively identified patients with cystic parathyroid adenomas who underwent surgery at Peking Union Medical College Hospital. Results Patients with cystic parathyroid adenomas had higher serum intact parathyroid hormone and calcium levels, larger maximum tumor diameter, and lower serum inorganic phosphorus level than did those with solid adenomas. Patients with cystic adenomas were predominantly male, and hypercalcemic crisis and atypical adenomas were common. The accuracy of preoperative localization methodologies was lower in patients with cystic adenomas than in patients with solid adenomas. US-guided fine-needle aspiration was performed in 11 patients. In all patients, the iPTH level in cystic fluid was much higher than that in serum. No sign of recurrence was observed after a median follow-up of 39 months. Conclusions Cystic parathyroid adenomas may not be as rare as previously reported. FNA may be a safe and feasible localization methodology for patients with inconclusive preoperative localization methodologies. Close follow-up is necessary for patients with cystic parathyroid adenomas, which account for a substantial proportion of atypical adenoma cases.

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Section: Discussionsupporting

confidence: 93%

The Clinical Features of Cystic Parathyroid Adenoma in Chinese Population: A Single-Center Experience

Cui

Xia

et al. 2018

International Journal of Endocrinology

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Effects of thyroid cystectomy for primary hyperparathyroidism on immune function

Yin¹,

Hu²,

Wang³

1969

Pak J Med Sci

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Objective:To evaluate the effects of thyroid cystectomy for primary hyperparathyroidism on immune function.Methods:Ninety-two patients with parathyroid cysts complicated with primary hyperparathyroidism were randomly divided into a treatment group and a control group (n=46). The treatment group received endoscopic thyroidectomy through the anterior chest wall via the areolar approach, and the control group was treated with conventional open thyroidectomy.Results:The two groups had similar immune function indices as well as thyroid hormone, serum calcium and phosphorus levels before surgery (P>0.05). After surgery, FT3 and FT4 levels significantly increased in both groups, whereas that of TSH significantly decreased (P<0.05). The levels of the two groups differed significantly on the postoperative 5th day (P<0.05). NK%, CD3+%, CD4+% and CD8+%, which significantly fluctuated on the postoperative 1st day in both groups (P<0.05), were basically recovered on the postoperative 5th day in the treatment group that had significantly different outcomes from those of the control group (P<0.05). On the postoperative 1st and 5th days, the treatment group had significantly lower serum calcium level and significantly higher serum phosphorus level than those of the control group (P<0.05). The surgeries were successfully performed for all patients. During three months of follow-up, the treatment group was significantly less prone to complications such as surgical site infection, recurrent laryngeal nerve injury, parathyroid crisis and hoarseness than the control group (P<0.05).Conclusion:For treatment of primary hyperparathyroidism, endoscopic thyroidectomy through the anterior chest wall via the areolar approach decreased the incidence rate of complications, as well as promoted the recovery of serum calcium and phosphorous levels, probably by only mildly affecting immune function and thyroid hormone levels.

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Primary hyperparathyroidism-related giant parathyroid adenoma (Review)

et al. 2021

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Primary hyperparathyroidism (PHPT), an endocrine condition caused by a parathyroid adenoma (PTA) in 80-85% of the cases, has shifted in the modern era to a mildly symptomatic phenotype due to the prompt recognition of hypercalcemia and to a minimally invasive surgical approach which has a curative potential. Clinical complications of PHTH are either related to high calcium or parathyroid hormone [also parathormone (PTH)] or both, while the originating tumor typically is small, without local mass effects. A distinct entity is represented by giant PTA (GPTA) which is considered at a weight of more than 3 (3.5) grams. The present article is a review of the literature involving practical points of non-syndromic PHPT-related GPTA. Most authors agree that pre-operatory calcium and PTH are higher in GPTA vs. non-GPTA. However, the clinical presentation of PHPT may be less severe, probably due to local mass effects that bring the patient to an early medical evaluation. Age distribution, sex ratio, rate of successful pre-operatory location do not differ from non-giant PTA. Hypovitaminosis D is more frequent in PTA of higher dimensions. Post-operative hypocalcemia, but not recurrent/persistent PHPT, is expected, even hungry bone disease. A higher rate of atypia is described although the tumor is mostly benign. Unusual presentations such as cystic transformation, initial diagnosis during pregnancy or auto-infarction have been reported. The ectopic localization of PTA presented in almost 15% of all cases may also be found in GPTA. What are the exact cutoffs for defining GPTA is still an open issue. Contents 1. Introduction 2. Aim 3. Giant parathyroid adenoma: Concept around the size considerations 4. Pre-operative biological correlates 5. Relationship with vitamin D status 6. Histological issues 7. Ectopic PTA of large dimensions 8. Risk of post-operative hypocalcemia 9. Future considerations 10. Conclusions

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Parathyroid Cyst Presenting as Acute Pancreatitis: Report of a Case

Cited by 3 publications

References 9 publications

The Clinical Features of Cystic Parathyroid Adenoma in Chinese Population: A Single-Center Experience

The Clinical Features of Cystic Parathyroid Adenoma in Chinese Population: A Single-Center Experience

Effects of thyroid cystectomy for primary hyperparathyroidism on immune function

Primary hyperparathyroidism-related giant parathyroid adenoma (Review)

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