Parathion-use of blood concentration to diagnose mortality of fish

Mount, Donald I.; Boyle, Harvey W.

doi:10.1021/es60034a012

Cited by 14 publications

(4 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Diazinon was also reported to cause scoliosis and hemorrhaging around the dorsal fin in exposed Motsugo fish Pseudorasbora parva (Kanazawa 1975). Vertebral displacement with localized hemorrhaging resulting from exposure to organophosphorus compounds have also been documented by Eaton (1970) Mount & Boyle (1969) for brown bullheads Ictalurus nebulosus. In most cases, the above mentioned displacements and hemorrhaging may be explained by the anticholinesterase action of the compounds inducing severe neuromuscular contractions which fracture the vertebrae.…”

Section: Discussionmentioning

confidence: 84%

Effects of temperature and salinity on Menidia beryllina embryos exposed to terbufos

Hemmer¹,

Middaugh²,

Moore³

1990

Dis. Aquat. Org.

View full text Add to dashboard Cite

Embryos of the inland silverside Menidia beryllina were exposed to the organophosphorus pesticide terbufos at 9 combinations of temperature (20, 25 and 30°C) and salinity (5, 12.5 and 20%.). Nominal exposure concentrations were 12.5, 25, 50 and 100 pg terbufos 1-' with an acetone and seawater control for each temperature/salinity combination. Test durations were temperature dependent and ranged from 5 to 14 d. Endpoints were embryo survival, hatching and percentage of larvae with normal vertebrae. Embryo survival was significantly ( a = 0.05) lower in tests conducted at 20°C for all salinities. Salinity affected survival only at combinations of 20%0 and 100 ~g terbufos I-' Both temperature and salinity affected the percentage hatch, wlth the lowest hatching occurring in tests at 20 "C and in tests conducted at 20 L. The percentage of larvae with normal vertebrae was significantly (a = 0.05) reduced from controls at terbufos concentrations of 25 (7 to 32 %), 50 (44 to 62 %) and 100 pg 1-' (58 to 73 %) for the 3 temperatures tested, whereas salinity showed no significant effect. Anomalies in the development of vertebrae occurred across all temperature and salinity combinations, and were observed at concentrations as low as 12.5 pg terbufos 1-'

show abstract

Section: Discussionmentioning

confidence: 84%

Effects of temperature and salinity on Menidia beryllina embryos exposed to terbufos

Hemmer¹,

Middaugh²,

Moore³

1990

Dis. Aquat. Org.

View full text Add to dashboard Cite

show abstract

“…Mount and Boyle [19] exposed the brown bullhead (Ictalurus nebulosus) to various concentrations of technical-grade parathion for time periods up to 30 d and observed a close relationship between concentration of parathion in the water and that in the blood. The residues in the exposed fish were directly proportional to the concentration of profenofos in water.…”

Section: Discussionmentioning

confidence: 99%

Profenofos Toxicity to the Eastern Rainbow Fish (Melanotaenia Duboulayi)

Kumar¹,

Chapman²

1998

Environ Toxicol Chem

View full text Add to dashboard Cite

The 96‐h median lethal concentration for profenofos in the Australian eastern rainbow fish (Melanotaenia duboulayi) was 0.9 mg/L, corresponding with an 83% reduction in acetylcholinesterase (AChE) activity in fish head. This is an order of magnitude less sensitive than the figure reported for crucian carp (Carassius carassius). Higher lethal body burdens were found in rainbow fish exposed to high concentrations of profenofos but the inhibition of AChE activity in these fish was less than in those killed by longer, normally sublethal, exposures. During sublethal exposure to 10 μg/L for 10 d, the fish accumulated profenofos residues of 5.3 mg/kg associated with a 70% reduction in AChE activity in fish head. Decreases in food intake, food conversion efficiency, and growth were observed at 10 d and significant loss of weight was noted at 21 d. These were associated with markedly increased swimming activity and response to light. A clear relationship existed between the depression of AChE activity and observed behavioral responses, such as swimming activity and food intake.

show abstract

“…The residues in the exposed fish were directly proportional to the concentration of profenofos in water. Mount and Boyle [19] exposed the brown bullhead ( Ictalurus nebulosus ) to various concentrations of technical‐grade parathion for time periods up to 30 d and observed a close relationship between concentration of parathion in the water and that in the blood. Bender [20] found that the uptake of malathion in flesh of common carp ( Cyprinus carpio ) was related to its concentration in water; 96‐h exposure to 1, 2.5, 5.0, and 7.5 mg/L malathion resulted in residues up to 0.9, 7.9, 28.4, and 41.6 mg/kg, respectively.…”

Section: Discussionmentioning

confidence: 99%

Profenofos toxicity to the eastern rainbow fish (Melanotaenia duboulayi)

Kumar

Chapman

1998

Enviro Toxic and Chemistry

View full text Add to dashboard Cite

Abstract-The 96-h median lethal concentration for profenofos in the Australian eastern rainbow fish (Melanotaenia duboulayi) was 0.9 mg/L, corresponding with an 83% reduction in acetylcholinesterase (AChE) activity in fish head. This is an order of magnitude less sensitive than the figure reported for crucian carp (Carassius carassius). Higher lethal body burdens were found in rainbow fish exposed to high concentrations of profenofos but the inhibition of AChE activity in these fish was less than in those killed by longer, normally sublethal, exposures. During sublethal exposure to 10 g/L for 10 d, the fish accumulated profenofos residues of 5.3 mg/kg associated with a 70% reduction in AChE activity in fish head. Decreases in food intake, food conversion efficiency, and growth were observed at 10 d and significant loss of weight was noted at 21 d. These were associated with markedly increased swimming activity and response to light. A clear relationship existed between the depression of AChE activity and observed behavioral responses, such as swimming activity and food intake.

show abstract

Parathion-use of blood concentration to diagnose mortality of fish

Cited by 14 publications

References 7 publications

Effects of temperature and salinity on Menidia beryllina embryos exposed to terbufos

Effects of temperature and salinity on Menidia beryllina embryos exposed to terbufos

Profenofos Toxicity to the Eastern Rainbow Fish (Melanotaenia Duboulayi)

Profenofos toxicity to the eastern rainbow fish (Melanotaenia duboulayi)

Contact Info

Product

Resources

About