Paraspinal calcinosis associated with progressive systemic sclerosis

Arginteanu, Marc S.; Perin, Noel I.

doi:10.3171/jns.1997.87.5.0761

Cited by 15 publications

(16 citation statements)

References 9 publications

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“…5a-c). In some patients, calcific deposits may produce compressions of the spinal cord or the nerve roots due to paraspinal location, especially at the cervical spine [13][14][15][16] or less frequently, due to intraligamentous location (Fig. 6a).…”

Section: Subcutaneous Involvement In Sscmentioning

confidence: 98%

Imaging features of musculoskeletal involvement in systemic sclerosis

et al. 2006

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This article describes the radiographic, sonographic and magnetic resonance (MR) features of musculoskeletal involvement in patients with systemic sclerosis (SSc). Conventional radiography is the traditional method of detecting digital calcifications, but ultrasonography (US) is also able to detect such calcifications before they appear on radiographs. MR imaging can be used to diagnose overlapping conditions (i.e., SSc and myositis or SSc and rheumatoid arthritis), and less frequently, to reveal neurologic complications of SSc. In patients with vascular ulcers, MR angiography is able to depict decreased flow within collateral digital arteries.

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Section: Subcutaneous Involvement In Sscmentioning

confidence: 98%

Imaging features of musculoskeletal involvement in systemic sclerosis

et al. 2006

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“…Initial presentations included occipital headaches, axial neck pain, neck stiffness, cervical radiculopathy and cervical myelopathy. 3,4,6,8,11,13 Our patient presented with an acute traumatic central cord syndrome after a hyperextension injury, precipitated by chronic stenosis from her dystrophic calcinosis.…”

mentioning

confidence: 99%

“…3,5,9 The disorder rarely inflicts the cervical spine; when it does, erosive, paraspinal, calcinosis may develop, which can produce spinal canal stenosis and instability. [3][4][5][6]10,11 There is an association between anti-centromere antibodies and calcinosis. 3,12 The calcinosis is generally dystrophic and is characterized by hydroxyapatite crystals.…”

mentioning

confidence: 99%

“…[3][4][5][6]10,11 There is an association between anti-centromere antibodies and calcinosis. 3,12 The calcinosis is generally dystrophic and is characterized by hydroxyapatite crystals. 8 The pathology may be propagated by microvascular insufficiency, inflammation and local tissue damage.…”

mentioning

confidence: 99%

“…2 Infrequently, systemic sclerosis can affect the spine through dystrophic calcinosis of the spinal column. [3][4][5][6][7] Several cases have documented destructive osteolysis of the posterior elements, causing spinal canal stenosis and spinal instability. 8 An association between this pathology with acute traumatic central cord syndrome and dural erosion is rare.…”

mentioning

confidence: 99%

See 2 more Smart Citations

Central cord syndrome in a patient with systemic sclerosis and cervical calcinosis: case report and review of literature

Nguyen

Sharma

Doan

et al. 2016

Spinal Cord Ser Cases

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Dystrophic calcinosis with both a huge calcified mass in the cervical spine and calcification in the chest wall in a patient with rheumatoid overlap syndrome

Nakamura¹,

Hirakawa

Takaoka³

et al. 2014

Clin Rheumatol

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Dystrophic calcinosis in soft tissue occurs in damaged or devitalized tissues in the presence of normal calcium and phosphorous metabolism. It is often noted in subcutaneous tissues in patients with collagen vascular diseases and may involve a relatively localized area or be widespread. A 74-year-old Japanese woman with an overlap of rheumatoid arthritis, Sjögren's syndrome, and systemic sclerosis developed a huge tumor-like mass at the atlanto-axial vertebral joint region that caused severe cervical pain and difficulty in activities of daily living. She also had subcutaneous dystrophic calcification in the soft tissue of the chest wall. Calcinosis associated with systemic sclerosis is a well-recognized phenomenon, but a destructive paraspinal tumor in the cervical spine associated with overlap syndrome is extremely unique. Because calcinosis in spinal locations can be complicated by neurological involvement, patients with progressive symptoms may require surgical intervention. Surgical resection and biological therapy improved this patient's life and activities of daily living. Calcinosis is common in the conditions reviewed here, and different agents have been used for treatment. However, calcinosis management is poorly organized and lacks an accepted classification, systematic studies, and clinical therapeutic trials. The association of calcinosis and collagen vascular diseases is clinically and etiologically important. Although a combination of calcinosis and rheumatoid overlap syndrome is rare, various collagen vascular diseases may occur simultaneously. A perceptive diagnostic approach toward these diseases is critical, and early diagnosis and treatment are needed to prevent dystrophic calcinosis.

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Paraspinal calcinosis associated with progressive systemic sclerosis

Cited by 15 publications

References 9 publications

Imaging features of musculoskeletal involvement in systemic sclerosis

Imaging features of musculoskeletal involvement in systemic sclerosis

Central cord syndrome in a patient with systemic sclerosis and cervical calcinosis: case report and review of literature

Dystrophic calcinosis with both a huge calcified mass in the cervical spine and calcification in the chest wall in a patient with rheumatoid overlap syndrome

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