2001
DOI: 10.1053/apmr.2001.25074
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Paraplegia secondary to Burkholderia pseudomallei myelitis: A case report

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Cited by 6 publications
(4 citation statements)
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“…Macroabscess formation carries a poor prognosis [12]. Paraplegia secondary to B. pseudomallei myelitis has been described [13]. Our patient also showed features of transverse myelitis with extensive cord involvement and paraplegia (Figures 2-5).…”
Section: Discussionsupporting
confidence: 50%
“…Macroabscess formation carries a poor prognosis [12]. Paraplegia secondary to B. pseudomallei myelitis has been described [13]. Our patient also showed features of transverse myelitis with extensive cord involvement and paraplegia (Figures 2-5).…”
Section: Discussionsupporting
confidence: 50%
“…Even though the presentation was an acute paralysis, he may have acquired the infection sometime prior to this presentation with gradual asymptomatic progression to a brief septicaemic phase with subsequent localization to psoas muscle. The exact pathogenesis of spinal cord melioidosis is not quite certain except in the cases where there is direct microbial invasion, which does not appear to be the case in our patient [6,7]. Probable hypotheses for this presentation would be direct compression of the spinal cord from the psoas abscess or vascular compromise of spinal cord secondary to thrombosis or septic embolisation from the infected psoas muscle or due to exotoxin induced myelitis and demyelination.…”
Section: Resultsmentioning
confidence: 65%
“…Cranial nerve palsies and unilateral limb weakness are frequently described in patients with neurologic melioidosis ( 6 , 7 , 9 , 13 , 14 ). Flaccid paraparesis, commonly documented in animals with B. pseudomallei infection, also has been reported in humans ( 6 , 10 , 15 ). Often, microscopic and macroscopic abscesses are evident, and a predilection of B. pseudomallei for the brainstem and spinal cord has been suggested ( 9 , 12 – 14 ).…”
mentioning
confidence: 87%
“…Neurologic abnormalities occur in 3%–5% of melioidosis cases, and more than one quarter of those are fatal ( 5 8 ). Many similarities have been described regarding the clinical features of neurologic melioidosis in naturally infected animals and humans and in animal models infected with B. pseudomallei ( 6 , 9 15 ). Cranial nerve palsies and unilateral limb weakness are frequently described in patients with neurologic melioidosis ( 6 , 7 , 9 , 13 , 14 ).…”
mentioning
confidence: 99%