Parapharyngeal space pleomorphic adenoma: A 30‐year review

Mendelsohn, Abie H.; Bhuta, Sunita; Calcaterra, Thomas C.; Shih, Hubert B.; Abemayor, Elliot; John, Maie A. St.

doi:10.1002/lary.20496

Cited by 44 publications

(13 citation statements)

References 20 publications

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“…There is close agreement among surgeons regarding the full excision of PAs as opposed to simply enucleating them, with mounting new evidence for ECD as being the preferred technique both in superficial parotid gland tumors and PPST [13], [14], [15], [16]. One of the major concerns about the use of ECD is the possibility of tumor spillage.…”

Section: Discussionmentioning

confidence: 99%

The Transcervical Approach for Parapharyngeal Space Pleomorphic Adenomas: Indications and Technique

et al. 2014

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BackgroundHead and Neck Parapharyngeal space tumors are rare. Pleomorphic Adenomas are the most common Parapharyngeal space tumors. The purpose of this study was to define preoperative criteria for enabling full extirpation of parapharyngeal space pleomorphic adenomas via the transcervical approach while minimizing functional and cosmetic morbidity.MethodsThe surgical records and medical charts of 19 females and 10 males with parapharyngeal space pleomorphic adenomas operated between 1993 and 2012 were reviewed.ResultsFifteen patients were operated by a simple transcervical approach, 13 by a transparotid transcervical approach, and one by a transmandibular transcervical approach. Complications included facial nerve paralysis, infection, hemorrhage and first bite syndrome. There were three recurrences, but neither recurrence nor complications were associated with the type of surgical approach.ConclusionA simple transcervical approach is preferred for parapharyngeal space pleomorphic adenomas with narrow attachments to the deep lobe of the parotid gland and for pleomorphic adenomas originating in a minor salivary gland within the parapharyngeal space.

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Section: Discussionmentioning

confidence: 99%

The Transcervical Approach for Parapharyngeal Space Pleomorphic Adenomas: Indications and Technique

et al. 2014

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“…Approximately, 80% of these neoplasms are benign [ 2 , 5 , 7 – 11 ]. Benign salivary gland tumors, and specifically pleomorphic adenoma, are most common, followed by neurogenic tumors [ 5 , 10 – 12 ]. Salivary gland neoplasms are also the most frequently found primary malignant tumors [ 3 , 5 , 7 , 10 ].…”

Section: Introductionmentioning

confidence: 99%

Tumors of the parapharyngeal space: the VU University Medical Center experience over a 20-year period

Hees

Weert

Witte

et al. 2018

Eur Arch Otorhinolaryngol

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BackgroundTumors of the parapharyngeal space (PPS) are rare, accounting for 0.5–1.5% of all head and neck tumors. The anatomy of the PPS is responsible for a wide variety of tumors arising from the PPS. This series of 99 PPS tumors provides an overview of the clinical course and management of PPS tumors.Materials and methodsThis retrospective study included clinical data from patients treated for PPS tumors from 1991 to 2012 (warranting at least a 4-year follow-up) at the VU University Medical Center, Amsterdam, The Netherlands.ResultsFifty percent were salivary gland tumors, 41% were neurogenic and 9% had a different origin. 18.2% of the PPS tumors were malignant. The most reported symptom at presentation was swelling of the neck and throat. In 14%, the PPS tumor was an accidental finding following imaging for other diagnostic reasons. Cytology showed an accuracy rate of 73.1% (19/26). The positive predictive value of a malignant cytology result was 86% (95% CI 42.1–99.6%). Surgery was performed in 55 patients (56%). The most frequently performed approach (56%) was the cervical–transparotid approach, followed by the cervical (25%), transmandibular (16%) and transoral (2%) approach. Nine patients died of the disease, of which seven patients had a malignant salivary gland tumor, one patient had a pleomorphic adenoma at first diagnosis which degenerated into carcinoma ex pleomorphic adenoma and one patient died of metastatic renal cell carcinoma.ConclusionThis large single-centre report on PPS tumors shows that careful diagnostic work up and proper surgical planning are important in this specific and rare group of head and neck tumors. Surgery was the main treatment (56%) for parapharyngeal tumors. Management of parapharyngeal neurogenic neoplasms generally consists of active surveillance due to peri-operative risk for permanent cranial nerve damage. The histopathological diagnoses were consistent with previous reports.

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“…Submucosal swelling in the lateral pharyngeal wall with or without extension to retromandibular fossa or the submandibular trigone are the classical findings of benign parapharyngeal swellings (12–16). PPS is a difficult place to clinical examination as it is surrounded by the muscles of mastication, mandible, and parotid gland.…”

Section: Discussionmentioning

confidence: 99%

Parotid Tail Pleomorphic Adenoma Extending to the Parapharyngeal Space

Polat

Doğan

Yüce

et al. 2013

Journal of Craniofacial Surgery

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Parapharyngeal space tumors are rare, accounting for 0.5% of head and neck neoplasms. Most of them are benign and originate in the salivary glands, especially the pleomorphic adenoma. We presented a 47-year-old male with parotid tail pleomorphic adenoma extending to the parapharyngeal space. The patient applied to our clinic with the complaints of a painless mass on his neck and in his mouth for three months. After fine needle aspiration biopsy the mass was diagnosed as pleomorphic adenoma. The patient hospitalized and operated in our clinic. As we see in literature review parapharyngeal space tumors are rare and most of them are pleomorphic adenomas arising from deep lobe of the parotid gland and extend into the PPS.

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Parapharyngeal space pleomorphic adenoma: A 30‐year review

Cited by 44 publications

References 20 publications

The Transcervical Approach for Parapharyngeal Space Pleomorphic Adenomas: Indications and Technique

The Transcervical Approach for Parapharyngeal Space Pleomorphic Adenomas: Indications and Technique

Tumors of the parapharyngeal space: the VU University Medical Center experience over a 20-year period

Parotid Tail Pleomorphic Adenoma Extending to the Parapharyngeal Space

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