volume 60, issue 5, P426-435 2016
DOI: 10.1590/2359-3997000000184
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Abstract: ABSTRACTObjective: Paraoxonase 1 (PON1) polymorphisms are associated with an increased susceptibility to cardiovascular disease. PON1 Q192R polymorphism (rs662) partially determine PON1 hydrolytic activity and protect against oxidation of LDL and HDL. This study aimed to delineate the association of PON1 status (functional 192 genotype and plasma activity levels) and atherogenicity in urbans residents aged 40 years or more. Materials and methods: Anthropometric data, lipid profiles, the atherogenic index of t…

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