Paraneoplastic psoriasis in a patient with prostate cancer

Cadmus, Simi D.; Pearlstein, Michelle V.; Pearlstein, Kevin A.; Jolly, Puneet S.

doi:10.1016/j.jdcr.2017.09.014

Cited by 4 publications

(1 citation statement)

References 8 publications

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“…Although it is well known that the onset or exacerbation of psoriasis can be influenced by specific factors such as infections ( 17 – 20 ) or drugs ( 21 ), internal malignancies as possible triggers are still disputed ( 22 , 23 ). In the current literature, only few authors describe an onset of psoriasis in a paraneoplastic context ( 24 , 25 ). This underlines the rarity and novelty of the case of paraneoplastic psoriasis in thymic carcinoma presented here.…”

Section: Discussionmentioning

confidence: 99%

Case Report: Paraneoplastic psoriasis in thymic carcinoma

Mix,

Knoll,

Häring

et al. 2023

Front. Oncol.

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Thymic carcinomas are exceedingly rare and very aggressive malignancies of the anterior mediastinum. While thymomas exhibit a high association with paraneoplastic syndromes, these phenomena are a rarity in thymic carcinomas. In general, acanthotic syndromes such as acroceratosis neoplastica and acanthosis nigricans maligna are commonly observed as paraneoplastic phenomena in patients with carcinomas. In contrast, psoriasis vulgaris, another acanthotic disease, rarely occurs as a paraneoplasia. We report the case of a 36-year-old patient with progressive thymic carcinoma (undifferentiated carcinoma, T3N2M1a) and paraneoplastic psoriasis occurring ten months before the initial diagnosis of the carcinoma. Over the course of the disease, new psoriatic flares heralded relapse or progression of the carcinoma. To our knowledge, this is the first reported case of paraneoplastic psoriasis in thymic carcinoma.

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