Paraneoplastic Pemphigus, Cicatricial Conjunctivitis, and Acanthosis Nigncans with Pachydermatoglyphy in a Patient with Bronchogem*c Squamous Cell Carcinoma

Lam, Sheridan; Stone, Mary Seabury; Goeken, James A.; Massicotte, Stephen J.; Smith, Ann Coleman; Folberg, Robert; Krachmer, Jay H.

doi:10.1016/s0161-6420(92)32030-5

Cited by 85 publications

(32 citation statements)

References 10 publications

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“…Anhalt and his colleagues described conjunctival erosions, pseudomembranous conjunctivitis and relentless conjunctival scarring with symblepharon formation, comparable to the findings in ocular cicatricial pemphigoid [1, 7, 8, 9]. …”

Section: Discussionmentioning

confidence: 69%

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Bilateral Corneal Melting in a Patient with Paraneoplastic Pemphigus

Beele

Claerhout²,

Kestelyn³

et al. 2001

Dermatology

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An 80-year-old man, with a solid abdominal tumor and multiple skin lesions, was admitted to the hospital because of a perforated right cornea and an impending perforation of the left. The clinical, histological, immunohistological and immunoprecipitation findings of the skin lesions were consistent with Anhalt’s criteria for paraneoplastic pemphigus (PNP). The underlying malignancy proved to be an incurable peripheral neuronal shaft tumor. Both conjunctivae appeared normal. The right eye revealed a flat anterior chamber, due to a spontaneous, central corneal perforation. The central part of the left cornea had severely thinned, resulting in a descemetocele, which eventually perforated. Multiple surgical interventions were needed to restore the anterior chamber in both eyes. Although a causative association between PNP and corneal perforation could not be demonstrated, we think that corneal melting should be added to the list of ocular complications in patients with PNP.

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Section: Discussionmentioning

confidence: 69%

“…Antibodies to the intercellular spaces, as seen in pemphigus vulgaris and pemphigus foliaceus, rarely lead to scarring. Therefore, Lam et al [9]suggested that conjunctival scarring in these cases might be induced by bacterial superinfections.…”

Section: Discussionmentioning

confidence: 99%

Bilateral Corneal Melting in a Patient with Paraneoplastic Pemphigus

Beele

Claerhout²,

Kestelyn³

et al. 2001

Dermatology

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“…The relationship between pemphi gus and internal malignancy has also been debated for a long time. These internal malignancies include chronic lymphocytic leukemia, bronchogenic squamous cell carci noma, benign thymoma and non-Hdgkin's lymphoma [3][4][5], However, there have been no reports on pemphigus patients associated with metastatic carcinoid. Recently, Anhalt et al [3] Carcinoid tumors are neoplasms of enterochromaffin cells.…”

Section: Discussionmentioning

confidence: 99%

Pemphigus Associated with Metastatic Carcinoid

Shirahama

Yagi²,

Furukawa³

et al. 1994

Dermatology

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“…Lung cancer has been reported in coexistence with wide range of ABD: PV [17,27,28], PNP [29], pemphigus vegetans [30,31], pemphigus herpetiformis [32], IgA pemphigus [33], BP [34] and MMP [35]. In some BP cases, tumor resection led to complete recovery [36] supporting the thesis of close interrelation of the diseases.…”

Section: Malignancies Associated With Abdmentioning

confidence: 97%