Paraneoplastic Palmar Fasciitis and Polyarthritis Syndrome in a Patient With Advanced Prostate Cancer

Nadal, Rosa; Antonarakis, Emmanuel S.

doi:10.1016/j.clgc.2013.05.008

Cited by 14 publications

(20 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Antineutrophil cytoplasmic antibodies and rheumatoid factor (RF) can be positive, but generally at low titres. PFPAS is therefore considered to be a seronegative syndrome . Radiographs of the joints appear generally normal, suggesting that PFPAS is a nonerosive form of arthropathy, while joint MRI and technetium‐99m bone scans may show nonspecific signs of arthritis such as synovial hyperaemia and joint oedema …”

Section: Reportmentioning

confidence: 99%

“…PFPAS is therefore considered to be a seronegative syndrome. 6 Radiographs of the joints appear generally normal, suggesting that PFPAS is a nonerosive form of arthropathy, while joint MRI and technetium-99m bone scans may show nonspecific signs of arthritis such as synovial hyperaemia and joint oedema. 7 PFPAS can mimic other conditions including scleroderma, Dupuytren contracture and rheumatoid arthritis (RA).…”

Section: Reportmentioning

confidence: 99%

See 1 more Smart Citation

Palmar fasciitis and polyarthritis, a rare paraneoplastic syndrome related to ovarian cancer

et al. 2017

View full text Add to dashboard Cite

Palmar fasciitis and polyarthritis syndrome (PFPAS) is an uncommon disorder characterized by diffuse inflammation of the palmar fascia, tendon sheaths, and joints of the fingers and wrists, which rapidly progresses to flexion contracture of the hands. This paraneoplastic syndrome, originally linked to ovarian carcinoma, has also been associated with multiple different malignancies. As PFPAS usually precedes the detection of cancer, its symptoms should raise the suspicion of an underlying malignancy and should be thoroughly investigated.

show abstract

Section: Reportmentioning

confidence: 99%

Section: Reportmentioning

confidence: 99%

Palmar fasciitis and polyarthritis, a rare paraneoplastic syndrome related to ovarian cancer

et al. 2017

View full text Add to dashboard Cite

show abstract

“…Palmer fasciitis and polyarthritis was first identified as a rare paraneoplastic syndrome in 1982 by Medsger et al . The syndrome is most commonly described with ovarian cancer, although other malignancies including pancreatic, gastric, prostate, lung, breast and uterine have been reported . The paraneoplastic syndrome can precede the diagnosis of cancer, occur simultaneously or as in this case be a sign of disease recurrence.…”

Section: Discussionmentioning

confidence: 99%

“…It has been proposed that the underlying mechanism is of fibrogenic growth factor production . Biopsies have revealed immunoglobulin deposition suggesting the cause involves an immune process …”

Section: Discussionmentioning

confidence: 99%

“…The syndrome typically responds poorly to anti‐inflammatories and steroids. Anti‐rheumatic drugs, including methotrexate, hydroxychloroquine, sulfasalazine and anti‐tumor necrosis factor, have been used with disappointing results . Treatment of the underlying malignancy has been effective for the inflammatory symptoms, although the palmar contractures usually persist …”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Paraneoplastic fasciitis and polyarthritis syndrome as a manifestation of breast cancer recurrence in a BRCA1 gene‐positive patient

Kennedy

Chapman

2015

Int J of Rheum Dis

View full text Add to dashboard Cite

Advances of autoimmune rheumatic diseases related to malignant tumors

Zhao,

Mi,

et al. 2023

Inflamm. Res.

View full text Add to dashboard Cite

Background Malignant neoplasms are a well-recognized global public health concern, with significant impacts on human health and quality of life. The interplay between tumors and autoimmune rheumatic diseases is complex, and the resulting tumor-associated rheumatic diseases represent a rare and intricate group of conditions that occur in the context of malignant tumors. In addition, various rheumatic diseases can arise as a consequence of oncology treatment. These diseases present with intricate clinical manifestations and pathological features, often rendering them challenging to diagnose and impacting patients' quality of life. Despite this, they have yet to be fully recognized. Methods This article presents a literature review of published original articles and review articles concerning paraneoplastic rheumatic syndromes and rheumatic diseases associated with cancer treatment. We conducted a comprehensive literature search in PubMed, Web of Science and Google Scholar databases, excluding duplicated and irrelevant studies. In cases of duplicated research, we selected articles with higher impact factors for the review. Results This review focuses on the clinical features, diagnosis, and treatment of paraneoplastic rheumatic diseases, as well as the pathogenesis of these diseases. Additionally, we summarize the autoimmune rheumatic diseases associated with cancer treatment. Ultimately, the goal of this review is to enhance recognition and improve the management of autoimmune rheumatic diseases related to tumors.

show abstract

Paraneoplastic Palmar Fasciitis and Polyarthritis Syndrome in a Patient With Advanced Prostate Cancer

Cited by 14 publications

References 27 publications

Palmar fasciitis and polyarthritis, a rare paraneoplastic syndrome related to ovarian cancer

Palmar fasciitis and polyarthritis, a rare paraneoplastic syndrome related to ovarian cancer

Paraneoplastic fasciitis and polyarthritis syndrome as a manifestation of breast cancer recurrence in a BRCA1 gene‐positive patient

Advances of autoimmune rheumatic diseases related to malignant tumors

Contact Info

Product

Resources

About