Paraneoplastic encephalitis associated with renal cell carcinoma

Abstract

Paraneoplastic encephalitis is a neurologic manifestation of paraneoplastic syndrome that can present as seizure, memory impairment, cognitive decline, behavior changes, gait disturbance, and/or psychiatric symptoms [1]. Classically, paraneoplastic encephalitis has been defined as the presence or high risk of cancer accompanied by certain neurologic symptoms including limbic encephalitis, encephalomyelitis, subacute cerebellar degeneration, and subacute sensory neuropathy, without any other causes [2]. Recent studies have found various autoan-

Síndrome de Capgras como manifestação de tumor renal

“…A ausência de marcadores inflamatórios na paciente, somada à lesão renal encontrada na tomografia, legitimam a associação dos sintomas neuropsiquiátricos com o provável tumor renal de células claras [7], que veio a ser confirmado posteriormente, por biópsia após nefrectomia.…”

“…Alguns tipos de tumor -como o carcinoma pulmonar de pequenas células e o timoma -são mais comumente associados à encefalite paraneoplásica [7,8]. Em contrapartida, o tumor renal de células claras não é classicamente associado a tal manifestação [8,9].…”

Paraneoplastički neurološki sindrom uz karcinom bubrega

“…Most neurologic PNS present as peripheral nervous system syndromes and myopathies, as shown in Table 1. Reports on central nervous system presentation are limited to anti-NMDAR and other limbic encephalitis, thus we present the first case of PNS associated with RCC which presented as severe form of Bickerstafflike brainstem encephalitis [2,[9][10][11][12][13][14][15] . Both conditions are antibody-mediated diseases treated with pulse dose methylprednisolone and TPE, which lead to temporal clinical response, as seen in our case.…”