Paraneoplastic demyelinating polyneuropathy associated with cardiac myxoma

Park, In‐Woo; Kim, Yong Gyun; Ro, Suho; Jeong, Yun Hyeong; Suh, Bum Chun

doi:10.1002/mus.26728

Cited by 2 publications

(2 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Just like Smith et al in their review of the literature [4], we found a sample of patients who had a myxoma diagnosis that initially presented as a PS [7][8][9][10][11][12][13][14][15][16][17][18]. Some articles suggest grouping PS by the nature of the symptoms they experience, whether they are arthritic, hematologic, neurologic, respiratory, gastrointestinal, or dermatologic.…”

Section: Discussionmentioning

confidence: 87%

Cardiac Myxomas As Chameleons: A Scoping Review of Their Paraneoplastic Presentations

Gil¹,

Cross²,

Barrera³

et al. 2023

Cureus

View full text Add to dashboard Cite

This scoping review aims to explore the relationship between cardiac myxomas (CMs) and paraneoplastic syndromes (PS). CMs are the most common tumors in the heart, with the majority located in the left atrium, and are often associated with a triad of obstructive, embolic, and constitutional symptoms. However, they can also present with unrelated symptoms that are part of a PS. This study performed a thorough literature search of 11 databases and included 12 papers in the final review. All of the patients were diagnosed with atrial myxoma, which initially presented as a PS. Surgery was the curative measure in all cases and resulted in remission in every case, with patients reporting resolution of symptoms at follow-up. The majority of patients in the study were female, with comorbid rheumatologic conditions often present. This study highlights the heterogeneity of presentations of CMs and their associated PS.

show abstract

Section: Discussionmentioning

confidence: 87%

Cardiac Myxomas As Chameleons: A Scoping Review of Their Paraneoplastic Presentations

Gil¹,

Cross²,

Barrera³

et al. 2023

Cureus

View full text Add to dashboard Cite

show abstract

“…Нередко наличие подобных проявлений трудно связать с исключительно доброкачественным течением опухоли сердца. Так, в 2019 г. описана демиелинизирующая полинейропатия в рамках паранеопластического синдрома при МС [10].…”

Section: Introductionunclassified

Heart myxoma under the mask of interstitial lung lesion: a difficult case from practice

et al. 2021

View full text Add to dashboard Cite

The aim of the investigation was to describe a clinical case of the development of interstitial lung lesions in a 57-year-old man with a large left atrial myxoma, which had a reverse development after myxomectomy.Materials and methods. Patient V., 57 years old, was hospitalized in the therapeutic department of the City Clinical Hospital No. 1 named after N. I. Pirogov in connection with bilateral polysegmental pneumonia. A month before hospitalization, he underwent an outpatient examination for progressive dyspnea. Myxoma of the heart was diagnosed. Due to the progression of respiratory failure and the appearance of fever, he was hospitalized. Amidst the multistage antibiotic therapy, there was a torpid course of lung pathology with syndromes of bilateral dissemination and “ground glass”, bilateral lymphadenopathy of the mediastinum, high pulmonary hypertension, and systemic inflammatory reaction syndrome. Thromboembolism of the branches of the pulmonary artery, tuberculosis, sepsis, infective endocarditis, neoplastic processes of pulmonary and other localization were excluded.Results. The clinical picture corresponded to interstitial lung lesions within the framework of paraneoplastic syndrome in heart myxoma. It was decided to urgently carry out myxomectomy.Conclusion. The clinical case demonstrates the development of a rare variant of paraneoplastic syndrome in left atrial myxoma, which was suspected during the patient’s treatment for bilateral polysegmental pneumonia. The progression of the pulmonary lesion was explained by active interstitial inflammation and was supported by the immunological activity of the heart tumor.The performed myxomectomy, despite the persisting syndrome of systemic inflammatory reaction and infiltration of the lung tissue, led in 2 weeks to complete resolution of interstitial lung lesions and pulmonary hypertension, which confirmed the causal relationship between myxoma of the heart and involvement in the pathological process of the lungs.

show abstract

Paraneoplastic demyelinating polyneuropathy associated with cardiac myxoma

Cited by 2 publications

References 7 publications

Cardiac Myxomas As Chameleons: A Scoping Review of Their Paraneoplastic Presentations

Cardiac Myxomas As Chameleons: A Scoping Review of Their Paraneoplastic Presentations

Heart myxoma under the mask of interstitial lung lesion: a difficult case from practice

Contact Info

Product

Resources

About