Paraneoplastic bullous pemphigoid: Clinical disease activity correlated with enzyme‐linked immunosorbent assay index for the NC16A domain of BP180

Song, Hee‐Jin; Han, Sung‐Hyup; Hong, Won-Kyu; Lee, Hyeon‐Sook; Shin, Jeonghyun; Choi, Gwang‐Seong

doi:10.1111/j.1346-8138.2008.00589.x

Cited by 5 publications

(1 citation statement)

References 6 publications

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“…6 A reduction of titres of BP 180 antibodies after surgical removal and chemotherapy with 5-FU for sigmoid carcinoma with concomitant diagnosis of BP, suggest that the BP is a paraneoplastic process. 7…”

Section: Discussionmentioning

confidence: 99%

A Case of Bullous Pemphigoid in a Patient with Dual Cancers, Fortuitous or Paraneoplastic?

Teo

Seah

2012

Ann Acad Med Singap

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Section: Discussionmentioning

confidence: 99%

A Case of Bullous Pemphigoid in a Patient with Dual Cancers, Fortuitous or Paraneoplastic?

Teo

Seah

2012

Ann Acad Med Singap

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Paraneoplastic Pemphigus and Autoimmune Blistering Diseases Associated with Neoplasm: Characteristics, Diagnosis, Associated Neoplasms, Proposed Pathogenesis, Treatment

et al. 2016

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Autoimmune paraneoplastic and neoplasm-associated skin syndromes are characterized by autoimmune-mediated cutaneous lesions in the presence of a neoplasm. The identification of these syndromes provides information about the underlying tumor, systemic symptoms, and debilitating complications. The recognition of these syndromes is particularly helpful in cases of skin lesions presenting as the first sign of the malignancy, and the underlying malignancy can be treated in a timely manner. Autoimmune paraneoplastic and neoplasm-associated bullous skin syndromes are characterized by blister formation due to an autoimmune response to components of the epidermis or basement membrane in the context of a neoplasm. The clinical manifestations, histopathology and immunopathology findings, target antigens, associated neoplasm, current diagnostic criteria, current understanding of pathogenesis, and treatment options for a selection of four diseases are reviewed. Paraneoplastic pemphigus manifests with clinically distinct painful mucosal erosions and polymorphic cutaneous lesions, and is often associated with lymphoproliferative neoplasm. In contrast, bullous pemphigoid associated with neoplasm presents with large tense subepidermal bullae of the skin, and mild mucosal involvement, but without unique clinical features. Mucous membrane pemphigoid associated with neoplasm is a disorder of chronic subepithelial blisters that evolve into erosions and ulcerations that heal with scarring, and involves stratified squamous mucosal surfaces. Linear IgA dermatosis associated with neoplasm is characterized by annularly grouped pruritic papules, vesicles, and bullae along the extensor surfaces of elbows, knees, and buttocks. Physicians should be aware that these autoimmune paraneoplastic and neoplasm-associated syndromes can manifest distinct or similar clinical features as compared with the non-neoplastic counterparts.

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Role of Dermal-Epidermal Basement Membrane Zone in Skin, Cancer, and Developmental Disorders

Marinkovich

2010

Dermatologic Clinics

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Paraneoplastic bullous pemphigoid: Clinical disease activity correlated with enzyme‐linked immunosorbent assay index for the NC16A domain of BP180

Cited by 5 publications

References 6 publications

A Case of Bullous Pemphigoid in a Patient with Dual Cancers, Fortuitous or Paraneoplastic?

A Case of Bullous Pemphigoid in a Patient with Dual Cancers, Fortuitous or Paraneoplastic?

Paraneoplastic Pemphigus and Autoimmune Blistering Diseases Associated with Neoplasm: Characteristics, Diagnosis, Associated Neoplasms, Proposed Pathogenesis, Treatment

Role of Dermal-Epidermal Basement Membrane Zone in Skin, Cancer, and Developmental Disorders

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