Parametrial tumour causing hydronephrosis and hydroureter due to IgG4 mediated retroperitoneal fibrosis; a laparoscopic resection

Silva, Dhammike; Randombage, Prabath; Gankanda, W.; Edirisinghe, R.; Mathanamohan, J.; Silva, Chandu De

doi:10.4038/cmj.v66i1.9360

Cited by 1 publication

(2 citation statements)

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“…IgG4-related disease is an uncommon condition in Sri Lanka, and only a handful of cases have been described among Sri Lankans. Based on our literature search, only one patient with IgG4related retroperitoneal disease has been published in Sri Lanka, causing parametrial disease [5]. We describe a patient with IgG4-related disease, causing fibro-inflammatory retroperitoneal disease and mass formation.…”

Section: Discussionmentioning

confidence: 96%

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Immunoglobulin G - 4(IgG4)-related disease: A case of retroperitoneal disease with mass formation

Subhani,

Sivapalan,

Dissanayake

2023

SL J. Med.

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IgG4-related disease is a rare cause of retroperitoneal fibrosis with mass formation. A 46-year-old female presented with lower back pain. She had an on-and-off mild fever and constitutional symptoms with evidence of tenderness over the lower back. Investigations revealed high inflammatory markers. Magnetic resonance imaging revealed an ill-defined signal area in the left paraspinal area. Histology revealed fibromuscular tissue with scattered plasma cells showing positivity for immunoglobulin-G-4 (IgG4). The immunomorphological features are suggestive of IgG4-related-retroperitoneal fibrosis. She was commenced on glucocorticoids. It is imperative to consider unusual diagnoses such as IgG4-related disease in a patient with retroperitoneal disease with evidence of mass formation.

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Section: Discussionmentioning

confidence: 96%

“…Very few IgG4-related disease: retroperitoneal disease Sri Lanka Journal of Medicine Vol. 32 No.2,2023 cases of patients with IgG4-related disease have been described in Sri Lanka [5]. We present a female patient in her forties with evidence of IgG4related retroperitoneal disease.…”

Section: Introductionmentioning

confidence: 91%