Parameters that help to differentiate biliary atresia from other diseases

Hayashida, Miyeko; Matsuura, Toshiharu; Kinoshita, Yoshiaki; Esumi, Genshiro; Yoshimaru, Koichiro; Yanagi, Yusuke; Takahashi, Yoshiaki; Taguchi, Tomoaki

doi:10.1111/ped.13392

Cited by 6 publications

(4 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…При невозможности подтвердить диагноз БА с использованием неинвазивных методов исследования, особенно в случаях наличия желчного пузыря в сочетании с ахоличным стулом, необходимо проводить интраоперационную холангиографию [34].…”

Section: диагностикаunclassified

Modern Approaches to the Surgical Treatment of Biliary Atresia

Разумовский

Ratnikov

2018

jour

View full text Add to dashboard Cite

The review of literature deals with the current classification of the biliary atresia, presents the authors’ opinion considering a technique of theKasaiprocedure, and displays modern modifications of portoenteroanastomosis estimating their effectiveness. PubMed database and Google Scholar search system were used to search for primary terms. Survival of children with this pathology was analyzed depending on theKasaitechnique, anatomical form, terms of portoenteroanastomosis and importance of early diagnosis of this pathology.

show abstract

Section: диагностикаunclassified

Modern Approaches to the Surgical Treatment of Biliary Atresia

Разумовский

Ratnikov

2018

jour

View full text Add to dashboard Cite

show abstract

“…This polymorphism is located in the stem region opposite to the mature miR-499 sequence and results in a change in the stem structure of miR-499. Compared with the A allele, the secondary structure for the G allele is less stable [ 8 ].…”

Section: Introductionmentioning

confidence: 99%

MicroRNA-499 rs3746444 polymorphism in Egyptian children with biliary atresia

Gawish¹,

El-Monem²,

El-Abd³

et al. 2020

ceh

View full text Add to dashboard Cite

“…ChE was relatively preserved in many cases, but an upward trend was observed in the first few months after initial PE, along with decreased T-Bil, AST, ALT, and γGTP, suggesting that ChE may be useful as a postoperative indicator. γGTP is known to be raised in BA patients but was considered to be potentially useful for following liver cell and bile duct epithelial damage and cholestasis because of its sensitivity [20,25]. In this study, it continued to remain high postoperatively irrespective of operative technique and took more than 5 years to reach normal levels.…”

Section: Discussionmentioning

confidence: 58%

“…There are several reports in the literature about postoperative SBM and prognosis [16,19,[24][25][26][27]. One assessed SNL subjects after OPE with SBM and another compared LPE with OPE using SBM, but both are less intensive than the current study; in the SNL paper only OPE subjects were reviewed for a few months after surgery with no comparison with 14 LPE [16] and in the paper comparing LPE and OPE with SBM, SNL subjects were not investigated specifically and the study period was for only 6 months after PE [28].…”

Section: Discussionmentioning

confidence: 99%

Biochemical Evaluation of Laparoscopic Portoenterostomy for Treating Biliary Atresia and Redo for Failed Portoenterostomy

Tsukui

Koga

Cazares

et al. 2022

Journal of Laparoendoscopic & Advanced Surgical Techniques

View full text Add to dashboard Cite

Background: Postoperative outcomes of portoenterostomy (PE) and redo-PE were evaluated using selected biochemical markers (SBM) and biochemical status categories (BSC). Methods: Subjects were 70 consecutive PE performed for biliary atresia. SBM were aspartate aminotransferase (AST)/alanine aminotransferase (ALT), cholinesterase (ChE), and platelet count (PLT) assessed at 1, 2, 3, 6, and 12 months, thence annually for a maximum of 10 years. BSC were: all SBM normal (N-SBM), normal AST/ALT (N-SLT), normal ChE (N-ChE), normal PC (N-PLT), all abnormal (A-SBM), abnormal AST/ALT (A-SLT), abnormal ChE (A-ChE), abnormal PC (A-PLT). Subjects achieving jaundice clearance (JC) and surviving with native livers (SNL) also had gamma glutamyl transpeptidase (γGTP) assessed. Redo-PE indicated for failed PE were assessed postoperatively using the same SBM/BSC protocol. Results: PE were laparoscopic (LPE; n=40) or open (OPE; n=30). Mean age/weight at PEand duration of follow-up were similar. For JC, LPE=34/40 (85.0%), OPE=22/30 (73.3%); p=0.23. For SNL, LPE=29/40 (72.5%), OPE=16/30 (53.3%); p=0.10. LPE and OPE were similar for SBM/BSC, except for a single significant increase in ALT in OPE at 6 months.Redo-PE was performed 17 to 180 days (mean 67.1 days) after primary PE. AST was significantly increased at the last pre-redo assessment 3 months after primary PE; p<0.05.After redo, AST decreased and SBM/BSC results were equivalent to non-redo subjects. Conclusion:Postoperative biochemical data for all PE cases were comparable; redo-PE would appear to be viable for restoring SBM, and AST could be valuable as a single marker of deterioration in redo cases.

show abstract

Parameters that help to differentiate biliary atresia from other diseases

Cited by 6 publications

References 13 publications

Modern Approaches to the Surgical Treatment of Biliary Atresia

Modern Approaches to the Surgical Treatment of Biliary Atresia

MicroRNA-499 rs3746444 polymorphism in Egyptian children with biliary atresia

Biochemical Evaluation of Laparoscopic Portoenterostomy for Treating Biliary Atresia and Redo for Failed Portoenterostomy

Contact Info

Product

Resources

About