Parameters of Off-Vertical Axis Rotation in Unilateral and Bilateral Vestibulopathy and Their Correlation with Vestibular Evoked Myogenic Potentials

Abstract

Off-vertical axis rotation (OVAR) is a laboratory test to assess the otolith function. This study aimed to analyze the parameters of OVAR in patients with unilateral vestibular hypofunction (UVH) and bilateral vestibulopathy (BVP), and to correlate the parameters of OVAR with those of VEMPs. Ten healthy volunteers, 41 UVH, and 13 BVP patients performed OVAR. Bias component (BIC) and modulation component (MOC) of UVH and BVP patients were compared with those of healthy controls. BIC and MOC were correlated with amplitude and interaural difference (IAD) of cervical VEMP (cVEMP) and ocular VEMP (oVEMP). In UVH patients, the direction of BICs to affected side rotation were reversed and the absolute value of BICs were decreased when they were compared to healthy controls. In BVP patients, BICs were markedly attenuated. MOCs were not changed in UVH and BVP patients. There was no statistically significant correlation between VEMPs and OVAR.

Effect of health education based on information-motivation-behavioral skills model on patients with unilateral vestibular dysfunction

“…Vestibular dysfunction (VH) is a common concomitant symptom in the late stages of a variety of peripheral vestibular lesions, and although the cause of VH may be traumatic, toxic, infectious, genetic, or neurodegenerative, the etiology is unknown in approximately 50% of cases[ 1 , 2 ]. Postural instability, blurred vision during head movements, dizziness, and imbalance can occur in the decompensated phase after vestibular function injury[ 3 ].…”