Parameter Estimation for Mixed-Mechanism Tear Film Thinning
Rayanne A. Luke,
Richard J. Braun,
Tobin A. Driscoll
et al.
Abstract:Etiologies of tear breakup include evaporation-driven, divergent flow-driven, and a combination of these two. A mathematical model incorporating evaporation and lipid-driven tangential flow is fit to fluorescence imaging data. The lipid-driven motion is hypothesized to be caused by localized excess lipid, or "globs." Tear breakup quantities such as evaporation rates and tangential flow rates cannot currently be directly measured during breakup. We determine such variables by fitting mathematical models for tea… Show more
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