Paralytic rabies following cat scratch and intra-dermal anti-rabies vaccination

Gowda, Vykuntaraju K.; Basavaraja, G V; Reddy, Hamsa; Ramaswamy, Premalatha

doi:10.4103/1817-1745.139328

Cited by 8 publications

(3 citation statements)

References 7 publications

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“…In contrast, exposure to a high virus titer, leads to direct infection of motor neurons whereas sensory neurons are probably not infected. Nevertheless, several cases of rabies following skin lesions have been reported [ 47 , 133 ], although it is not clear whether sensory neurons were infected in those cases. It is possible that different genotype 1 lyssaviruses have differential tropism for sensory neurons and epidermal cells [ 85 ].…”

Section: Flaviviridaementioning

confidence: 99%

Neurotropic virus infections as the cause of immediate and delayed neuropathology

et al. 2015

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A wide range of viruses from different virus families in different geographical areas, may cause immediate or delayed neuropathological changes and neurological manifestations in humans and animals. Infection by neurotropic viruses as well as the resulting immune response can irreversibly disrupt the complex structural and functional architecture of the central nervous system, frequently leaving the patient or affected animal with a poor or fatal prognosis. Mechanisms that govern neuropathogenesis and immunopathogenesis of viral infections are highlighted, using examples of well-studied virus infections that are associated with these alterations in different populations throughout the world. A better understanding of the molecular, epidemiological and biological characteristics of these infections and in particular of mechanisms that underlie their clinical manifestations may be expected to provide tools for the development of more effective intervention strategies and treatment regimens.Electronic supplementary materialThe online version of this article (doi:10.1007/s00401-015-1511-3) contains supplementary material, which is available to authorized users.

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Section: Flaviviridaementioning

confidence: 99%

Neurotropic virus infections as the cause of immediate and delayed neuropathology

et al. 2015

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“…In fact, there are numerous studies that report that most of the rabies suspected exposures is due to dogs [25,26]. However, a small number of cases who died from rabies after being scratched by cats were also reported [27]. Therefore, it was determined that the causes of increased suspected exposure due to cat contact cases should be investigated and a separate attention should be paid to cats in activities such as education and vaccination.…”

Section: Discussionmentioning

confidence: 99%

An increasing public health problem: Suspected rabies exposures

Porsuk¹,

Cerit

2021

J Infect Dev Ctries

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Introduction: The increasing trend of rabies suspected exposures is a serious public health problem that is challenging the health systems of developing countries both in terms of labor and economics. The purpose of our study is to determine the current state of rabies suspected exposure cases. Methodology: This descriptive and cross-sectional study was conducted by retrospectively examining the applications made due to suspected exposures to a state hospital’s emergency service in Turkey. Descriptive and analytical statistics were used in data analysis and p ≤ 0.05 was considered as statistically significant. Results: Between 2015 and 2019, 3,378 hospital admissions due to suspected exposures were detected (n = 3,378). The number of admissions, which was 558 in 2015, increased every year and reached 829 in 2019 (p < 0.001). Also admissions after contact with cats have increased over the years and have passed contact with dogs in 2019 (p < 0.001). Post-exposure prophylaxis was applied to all cases, but 0.8% (n = 26) of them were found to be inappropriate according to guidelines. It was observed that 38.3% of overall cases examined were individuals aged 19 and under. It was also observed that 69.1% (n = 2,326) of the suspected exposures were caused by owned animals (p < 0.001). Conclusions: The case rates seen in children indicate the need for special studies for children. Applications for suspected exposures due to contact with cats were found to be a growing problem. Therefore, it was concluded that the patterns of rabies suspected exposure cases in Turkey and similar developing countries should be monitored regularly and measures should be taken according to local needs. Besides, stray animals in cities must be minimized and all animals living in cities owned or stray, must be monitored in terms of vaccination.

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“…Because the son did not receive immediate RIG treatment, he remained at possible risk for RV infection [ 9 , 10 ]. RVNA of the son has been actively monitored; his health condition has been assessed every 6 months post his initial result.…”

Section: Case Presentationmentioning

confidence: 99%

Bites from the same dog, different outcomes for two patients: a case report

Huang

et al. 2017

Infect Dis Poverty

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BackgroundRabies is a serious reemerging zoonosis in China. At present human rabies cases are primarily diagnosed based on clinical presentation.Case presentationIn August 2012, a woman and her son were attacked by a stray dog in Henan, China. The son received rabies postexposure prophylaxis (wound treatment followed by vaccine, no immunoglobulin), however, the mother did not. Rabies infection was subsequently laboratory confirmed in the mother and she died in December; her son is alive and healthy after 2 years of follow-up.ConclusionThis report documents that the timely utilization of postexposure prophylaxis is a required measure in preventing rabies after exposure to an animal bite.Electronic supplementary materialThe online version of this article (doi:10.1186/s40249-017-0321-3) contains supplementary material, which is available to authorized users.

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Paralytic rabies following cat scratch and intra-dermal anti-rabies vaccination

Cited by 8 publications

References 7 publications

Neurotropic virus infections as the cause of immediate and delayed neuropathology

Neurotropic virus infections as the cause of immediate and delayed neuropathology

An increasing public health problem: Suspected rabies exposures

Bites from the same dog, different outcomes for two patients: a case report

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