Paralysis caused by “nagging”

Peripheral neuropathy following nitrous oxide abuse

“…Another recent case report on paralysis attributed to N2O abuse was associated with number of serious medical complications including cardiac arrest with relatively lower N2O bulb use than in other case reports. 9 Although her neurological findings were attributed to N2O abuse and malnutrition, this conclusion would have been unequivocally justified if MMA or HC levels had been measured.…”

Neurologic, psychiatric, and other medical manifestations of nitrous oxide abuse: A systematic review of the case literature

“…Arshi and Shaw 65 21 yo M Numbness, imbalance B12: #-nl, HCY: " Bhavsar and Khurana 66 23 yo F Paresthesias, gait imbalance B12: #; HCY: "; MMA: "; MCV: nl Blanco and Peters 67 30 yo M Difficulty walking, paresthesias, headaches, painful erections, low libido, poor memory B12: #; MCV: "; Schill: nl Brett 68 21 yo F Weakness, falls, anxiety B12: #-nl Butzkueven and King 69 23 yo M Paresthesias, unsteady gait, incoordination B12: #; MCV: " Cartner et al 70 20 yo F Difficulty moving B12: #; MCV: nl Cheng et al 71 22 yo F Progressive foot tingling and poor balance B12: #; MMA: "; MCV: nl Chiang et al 72 29 yo F Numbness, weakness, unsteady gait, skin hyperpigmentation B12: #; HCY: "; MCV: nl Diamond et al 73 31 yo M Paresthesias B12: #; HCY: "; MCV: nl Duque et al 74 20 yo F Paresthesias, difficulty walking B12: #; MMA: "; MCV: nl Durrani et al 75 79 19 yo M Limb numbness, gait instability B12: #; MCV: " Hu et al 80 16 yo F Numbness, sensory ataxia B12: #-nl; HCY: nl; MCV: " Huang et al 81 19 yo F Weakness, ataxia, inability to walk n/r Iwata et al 82 55 yo M AMS, gait problems B12: #; MCV: " Jones et al 83 18 yo F Numbness, weakness, foot drop B12: nl; MMA: nl Lai et al 84 24 yo F Numbness, paresthesias, weakness B12: # Layzer et al 29 86 35 yo F Paresthesias, difficulty walking B12: #-nl; MCV: nl; HCY: "; MMA: " Lin et al 87 41 yo M Paresthesias, Lhermitte's sign B12: #; MCV: "; Schill: nl Lin et al 88 : Case 1 24 yo M Numbness, weakness, unsteady gait B12: #; MCV: " Lin et al 88 : Case 2 18 yo F Tingling, numbness, weakness, unsteady gait B12: #-nl; HCY: ", MCV: "…”

Nitrous oxide‐induced neurological disorders: an increasing public health concern

“…Nitrous oxide (N 2 O) is a colourless, non‐flammable gas that has long been used as a dissociative anaesthetic agent 1 . Since its discovery, there have been reports of recreational use (colloquially referred to as ‘nagging’ or ‘nanging’) due to the brief dissociative, euphoric and hallucinogenic effects 1–7 . There has been a notable rise in use of N 2 O recreationally in recent years.…”