Paralysie faciale associée à la leptospirose

Lahsen, A. Oulad; Rachidi, T.; Sodqi, M.; Abada, R.; Marhoum, K. Elfilali

doi:10.1016/j.medmal.2010.04.010

Cited by 4 publications

(1 citation statement)

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“…A wide range of clinical manifestations were reported including febrile illness, jaundice, meningitis, and acute respiratory distress syndrome. Case reports described confirmed or probable acute leptospirosis in patients in South Africa (n = 6) [ 43 , 47 , 54 , 57 , 65 , 71 ], Gabon (n = 3) [ 48 , 62 , 76 ], Morocco (n = 3) [ 50 , 52 , 53 ], Algeria (n = 1) [ 32 ], Mali (n = 1) [ 51 ], Réunion (n = 1) [ 75 ], and Senegal (n = 1) [ 60 ]. With the exception of Réunion and Senegal, case reports were the only eligible data on acute human leptospirosis from these countries.…”

Section: Resultsmentioning

confidence: 99%

Epidemiology of Leptospirosis in Africa: A Systematic Review of a Neglected Zoonosis and a Paradigm for ‘One Health’ in Africa

et al. 2015

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BackgroundLeptospirosis is an important but neglected bacterial zoonosis that has been largely overlooked in Africa. In this systematic review, we aimed to summarise and compare current knowledge of: (1) the geographic distribution, prevalence, incidence and diversity of acute human leptospirosis in Africa; and (2) the geographic distribution, host range, prevalence and diversity of Leptospira spp. infection in animal hosts in Africa.MethodsFollowing Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines, we searched for studies that described (1) acute human leptospirosis and (2) pathogenic Leptospira spp. infection in animals. We performed a literature search using eight international and regional databases for English and non-English articles published between January 1930 to October 2014 that met out pre-defined inclusion criteria and strict case definitions.Results and DiscussionWe identified 97 studies that described acute human leptospirosis (n = 46) or animal Leptospira infection (n = 51) in 26 African countries. The prevalence of acute human leptospirosis ranged from 2 3% to 19 8% (n = 11) in hospital patients with febrile illness. Incidence estimates were largely restricted to the Indian Ocean islands (3 to 101 cases per 100,000 per year (n = 6)). Data from Tanzania indicate that human disease incidence is also high in mainland Africa (75 to 102 cases per 100,000 per year). Three major species (Leptospira borgpetersenii, L. interrogans and L. kirschneri) are predominant in reports from Africa and isolates from a diverse range of serogroups have been reported in human and animal infections. Cattle appear to be important hosts of a large number of Leptospira serogroups in Africa, but few data are available to allow comparison of Leptospira infection in linked human and animal populations. We advocate a ‘One Health’ approach to promote multidisciplinary research efforts to improve understanding of the animal to human transmission of leptospirosis on the African continent.

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