Abstract:Nowadays, next generation sequencing is closer to clinical application in the field of oncology. Indeed, it allows the identification of tumor-specific mutations acquired during cancer development, progression and resistance to therapy. In parallel with an evolving sequencing technology, novel computational approaches are needed to cope with the requirement of a rapid processing of sequencing data into a list of clinically-relevant genomic variants.Since sequencing data from both tumors and their matched norma… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.