Parallel evolution of linezolid-resistant
Staphylococcus aureus
in patients with cystic fibrosis
Nicholas J. Pitcher,
Andries Feder,
Nicholas Bolden
et al.
Abstract:Linezolid is an antibiotic used to treat serious
Staphylococcus aureus
infections. Resistance to linezolid is considered rare but could emerge with repeated dosing. We recently reported widespread prescription of linezolid for a cohort of patients with cystic fibrosis (CF). The goals of this study were to determine the incidence of linezolid-resistant methicillin-resistant
Staphylococcus aureus
(MRSA) in CF and identify molecular mechanisms for linezolid resistan… Show more
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