Paralisia residual pós-operatória

Mathias, L; Bernardis, Ricardo Caio Gracco de

doi:10.1590/s0034-70942012000300016

Cited by 4 publications

(10 citation statements)

References 70 publications

(70 reference statements)

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“…The loss of the fourth response corresponds to 75-80% of the first stimulus block. The disappearance of the third, second and first contractions corresponds to the blockade of about 85%, 90% and 98-100%, respectively [1,3].…”

Section: Introductionmentioning

confidence: 96%

“…Values of the T4/T1 ratio below 0.9 evaluate worsening of the ventilatory response to hypoxia and the function of the pharyngeal and upper esophageal sphincter muscles, predisposing to pulmonary aspiration and ventilatory complications. In incomplete depolarizing blockade, because no fatigue occurs, the four responses are practically identical, which maintains the T4/T1 ratio between 0.9 and 1.0 [1,3].…”

Section: Introductionmentioning

confidence: 99%

“…They act to produce relaxation of the muscles, facilitating tracheal intubation and providing good surgical conditions. In addition, they can be used during cardiopulmonary resuscitation and in intensive care units in mechanical ventilation [1,2].…”

Section: Introductionmentioning

confidence: 99%

“…Such a situation alters the permeability of the membrane to ions such as potassium and sodium, which diminishes the action potential propagated by the muscular fibers, occurring the muscular contraction. According to the mechanism and duration of action, they are classified as agonist ("depolarizing" BNMs) and nicotinic receptor antagonists ("NMDs"), being these subclassed into long-acting, intermediate and short-acting drugs [1,2,4].…”

Section: Introductionmentioning

confidence: 99%

“…The literature generally indicates that adequate tracheal intubation requires at least two effective doses of any of the BNMs. The intubation conditions clinically acceptable by direct laryngoscopy are: Relaxed jaw, open and immobile vocal cords and absence of diaphragmatic movements [1,2].…”

Section: Introductionmentioning

confidence: 99%

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Incidence of Residual Neuromuscular Blocking in Oncological Patients in the Anesthetic Rescue Room: Importance of Objective Monitoring in the Foundation Center of Control of Oncology of the State of Amazonas - Fcecon

Pirangy¹,

Melo²,

Pereira³

et al. 2019

Int J Anesthetic Anesthesiol

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The present research project aims to evaluate the incidence of residual neuromuscular block in the post-anesthetic recovery room in patients who underwent general anesthesia with mechanical ventilation. It is known that neuromuscular blockers are drugs that interrupt the transmission of nerve impulses at the neuromuscular junction causing muscle paralysis. In addition, they facilitate endotracheal intubation during anesthetic induction and allow for adequate surgical management.There are several adverse effects resulting from their use, among them: The occurrence of vagolytic and sympatholytic activities that cause cardiovascular alterations or autonomic stimulation. Monitoring the levels of these blockers is of paramount importance because it allows the titration of the drug. By relaxing and paralyzing the muscles, postoperative weakness due to the absence or incomplete performance of the antagonists of this drug is frequent. This situation is known as postoperative residual neuromuscular block.When it comes to the anesthetic practice to evaluate such situation, the patient's clinic is often the only alternative. The safe use of neuromuscular blockers requires monitoring to qualify muscle relaxation by being measured from a known monitor of four stimuli or Train of Four (TOF).The residual neuromuscular blocker influences possible clinical complications that may lead to increased morbidity and mortality in the postoperative period. Thus, this project aims to identify the incidence of residual neuromuscular block in the postanesthetic recovery room in order to reduce the cardiorespiratory complications resulting from the use of the adenos polarizing neuromuscular blockers.

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Section: Introductionmentioning

confidence: 96%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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