Paralisia facial bilateral e leucemia mielóide aguda: uma associação pouco comum

Abstract

A leucemia mielóide aguda (LMA) é uma doença maligna do tecido hematopoiético. A apresentação da doença pode estar relacionada com a perda de função da medula óssea ou com sintomas gerais das doenças neoplásicas. O envolvimento extra-medular é responsável por formas de apresentação menos frequentes que podem dificultar um diagnóstico precoce. A hipertrofia gengival não é incomum na LMA mas os casos de paralisia facial bilateral são raros. Neste artigo os autores apresentam o caso de um homem de 70 anos que surge com hipertrofia gengival que inicialmente não é valorizada e que desenvolve, após três semanas, uma paralisia facial periférica bilateral. O mielograma revelou uma LMA. Com a quimioterapia dirigida o doente entrou em remissão completa mas manteve a sintomatologia de apresentação da doença.

Oral Hygiene and Pocket Depth among Acute Myeloid Leukemic Adult Patients in Erbil City

“…Other studies determined that incidence of AML is rare under the age of 40 but rises with age, from around 1 per 100,000 at age 40 to more than 15 per 100,000 at age 75 and older [26,27].According oral hygiene; majority of control group in the present study were had excellent oral hygiene (61.42 %) while majority of AML group had bad oral hygiene (58.57%) this may be due to the fact that the patients avoided brushing for fear of bleeding or due to reduce salivary secretion due to chemotherapy . This study is in agreement with another study in which it's explored that around three-quarters of the patients had either fair or poor oral hygiene [10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28].…”

“…Pathologic changes observed in gingival enlargement is Collection of connective tissue with the increased number of cells. Gingival enlargement can be categorized according to the causative factors as inflammatory, drug-induced, neoplastic, false enlargement, and is usually related to systemic diseases especially granulomatous diseases and leukemia [10][11][12].…”

“…The occurrence of gingivitis/periodontitis (poor oral health) can be exhibited in leukemic patients undergoing chemotherapy [13]. Poor hygiene can be considered one of the risk factors for leukemic gingival overgrowth and destructive periodontal disease in which can be manifested by oral pain, hemorrhage, and superinfection, and malaise, pain, fever, laryngeal, and cervical lymphadenopathy can be experienced in severe cases [10][11][12][13][14].…”