Paragonimiasis: Diagnosis and the Use of Praziquantel in Treatment

Johnson, Richard J.; Jong, Elaine C.; Dunning, Steven B.; Carberry, William L.; Minshew, Barbara H.

doi:10.1093/clinids/7.2.200

Cited by 59 publications

(19 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The alternative agent, praziquantel, has proven to be effective for paragonimiasis. 15,16 Headache, nausea, and urticaria have been reported as adverse effects during its use. 15 Our study confirmed that praziquantel treatment, 75 mg/kg/d for 2 to 3 days, was very useful and safe.…”

Section: Discussionmentioning

confidence: 99%

Clinicoradiologic Features of Pleuropulmonary Paragonimus westermani on Kyusyu Island, Japan

Mukae

Taniguchi

Matsumoto

et al. 2001

Chest

127

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Clinicoradiologic Features of Pleuropulmonary Paragonimus westermani on Kyusyu Island, Japan

Mukae

Taniguchi

Matsumoto

et al. 2001

Chest

127

View full text Add to dashboard Cite

“…7), they are usually not seen in the pleural fluid. Leukocytes, eosinophils, and Charcot-Leyden crystals are commonly seen in the pleural fluid; these crystals are birefringent and may be easily visualized using plane-polarized light (76,78). The examination of the pleural fluid from one patient with North American paragonimiasis demonstrated a WBC count of 2,900/l, 93% of which were eosinophils.…”

Section: General Laboratory Findingsmentioning

confidence: 99%

North American Paragonimiasis (Caused by Paragonimus kellicotti ) in the Context of Global Paragonimiasis

2009

View full text Add to dashboard Cite

SUMMARY Paragonimus species are highly evolved parasites with a complex life cycle that involves at least three different hosts, i.e., snails, crustaceans, and mammals. The adult forms of Paragonimus species reside and mate in the lungs of a variety of permissive mammalian hosts, including humans. Although human paragonimiasis is uncommonly encountered in North America, both autochthonous and imported disease may be encountered. Paragonimus kellicotti, the species endemic to North America, is a well-known pathogen in wild and domestic animals. Five patients with North American paragonimiasis have been reported in the recent medical literature. The biologic, clinical, radiologic, and laboratory features of paragonimiasis are reviewed, with emphasis on North American paragonimiasis whenever possible.

show abstract

“…Praziquantel can damage the cortex of parasites and stimulate muscle tonic contraction, causing spastic paralysis and death, and is recommended as an orally administered agent at a total dose of 75-150 mg/kg (13). The cure rate is 80-90%, with infrequent side effects (14).…”

Section: Discussionmentioning

confidence: 99%

Paragonimiasis mimicking chest cancer and abdominal wall metastaisis: A case report

et al. 2016

View full text Add to dashboard Cite

Abstract. Typical human paragonimiasis demonstrates an elevated eosinophil count, positive immunoblot, nodular shadows of the lung and pleural thickening with pleural effusion, and these symptoms may be confused with chest cancer. In the present case, a rare case of human paragonimiasis mimicking chest cancer and abdominal wall metastasis is described, the 39-year-old male patient was admitted in our hospital for cough, weight loss 5 kg and a firm mass in right upper abdominal wall. The laboratory test showed unremarkable hematology and biochemistry results. Chest X-ray, Plain computed tomography of the chest and abdomen showed right pleural effusion, several nodules in right lower lung and a mass in the right upper abdominal wall. The initial diagnosis was lung or chest cancer with abdominal wall metastasis, and the abdominal wall mass was resected for the final diagnosis. The biopsy revealed eosinophilic granuloma with Charcot-Leyden crystal formation infiltrated in the muscular fibers. Subsequent to assessment of the antibodies against parasites, the final diagnosis of paragonimiasis was made.

show abstract

Paragonimiasis: Diagnosis and the Use of Praziquantel in Treatment

Cited by 59 publications

References 28 publications

Clinicoradiologic Features of Pleuropulmonary Paragonimus westermani on Kyusyu Island, Japan

Clinicoradiologic Features of Pleuropulmonary Paragonimus westermani on Kyusyu Island, Japan

North American Paragonimiasis (Caused by Paragonimus kellicotti ) in the Context of Global Paragonimiasis

Paragonimiasis mimicking chest cancer and abdominal wall metastaisis: A case report

Contact Info

Product

Resources

About