Paraganglioma of the Urinary Bladder: A Case Report on a Rare and Unexpected Tumor Location

Kratiras, Z.; Kaltsas, Aris; Koufopoulos, Nektarios; Adamos, Konstantinos; Chrisofos, Michael

doi:10.7759/cureus.41998

Cited by 3 publications

(4 citation statements)

References 15 publications

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“…This finding is unusual for pheochromocytomas, as elevated levels of metanephrines and normetanephrines are usually detected in these cases [ 2 , 9 ]. The combination of the rarity of PUB and the lack of specific symptoms can render the diagnosis particularly challenging [ 10 ]. The normal hormonal test results in our patient emphasize the importance of maintaining a high index of suspicion and relying on a combination of clinical presentation, imaging, and cystoscopic findings for the diagnosis of PUB.…”

Section: Discussionmentioning

confidence: 99%

Bladder Paraganglioma Presenting as Post-Micturition Palpitations: A Case Report

Zare,

Bighamian,

Moloudi

et al. 2024

Case Rep Oncol

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Introduction: Paraganglioma of the urinary bladder (PUB) is an extremely rare extra-adrenal catecholamine-secreting neuroendocrine tumor, accounting for only 0.05% of all bladder tumors and 1% of all pheochromocytomas. The clinical presentation of PUB can be diverse and challenging to diagnose. Case Presentation: This case report presents a 37-year-old man with post-micturition palpitation, headache, and sweating, with no history of hematuria or other irritative urinary symptoms. Ultrasound and contrast-enhanced computed tomography revealed a suspicious mass in the right posterolateral wall of the urinary bladder. Despite normal functional hormonal tests, the diagnosis of PUB was confirmed after surgical enucleation and histopathological examination. Conclusion: This report emphasizes the importance of considering PUB as a differential diagnosis in patients with post-micturition symptoms and paroxysmal hypertension, as well as the need for a multidisciplinary approach in the evaluation and management of such rare and complex cases. Early recognition and surgical intervention are crucial for optimal management and favorable clinical outcomes.

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Section: Discussionmentioning

confidence: 99%

Bladder Paraganglioma Presenting as Post-Micturition Palpitations: A Case Report

Zare,

Bighamian,

Moloudi

et al. 2024

Case Rep Oncol

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“…These tumours are of neural crest origin and arise from the chromaffin cells in the bladder wall. 3,6,7 Das et al reported that the commonest presentations of a bladder paraganglioma can range from macroscopic haematuria to severe uncontrolled hypertension leading to seizures upon micturition. 8 Certain stimuli have been identified, pertaining to these unusual tumours.…”

Section: Discussionmentioning

confidence: 99%

Paraganglioma of the urinary bladder- a case report

Hassan,

Quereshi

2024

J Pak Med Assoc

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It is very uncommon to discover Paragangliomas in the urinary bladder. These tumours originate from the sympathetic nerves which supply chromaffin cells in the bladder wall. They can be classified as functional or non-functional. If functional, the most common presentations are with hypertensive crisis or post-micturition syncope. A silent paraganglioma of the bladder can be easily misdiagnosed which can result in severe peri-operative morbidity. We present a case of a male patient who was being managed for hypertension for 2-3 years. He presented at The Indus Hospital, Karachi on 7th August 2022 with gross painless haematuria. An ultrasound scan revealed an echogenic lesion arising from base of the urinary bladder, which was treated via Transurethral Resection of Bladder Tumour (TURBT). Histopathological report revealed Paraganglioma of the Bladder. He was later scheduled for Partial Cystectomy (PC) and has been doing well ever since.

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“…In light of these findings, the key message we wish to convey is the necessity for urologists to maintain a high level of vigilance and a strong index of clinical suspicion for any bladder mass [5]. Even in the face of nonspecific symptoms and a negative lab or imaging workup, prompt diagnostic cystoscopy should not be delayed, enabling timely management [17].…”

Section: Discussionmentioning

confidence: 99%

“…Such bladder lipomas have been infrequently documented in the medical literature due to their nonspecific clinical presentation, often diagnosed via endoscopic biopsy, with further excision for clinical management typically not required [4]. This case report presents a unique instance of bladder lipoma in a patient presenting with gross hematuria, emphasizing the need for increased clinical awareness and consideration in differential diagnoses, which have also been described within the urinary bladder [5,6].…”

Section: Introductionmentioning

confidence: 85%

An Atypical Case of Bladder Lipoma Presenting as Gross Hematuria: A Case Report

Kaltsas¹,

Zachariou²,

Tien³

et al. 2023

Cureus

Self Cite

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While conventional lipomas represent the most commonly seen benign mesenchymal tumor in adults, their occurrence in the bladder wall is exceptionally rare. This report details a rare case of a bladder lipoma, a benign tumor primarily composed of mature adipocytes, presenting as gross hematuria in a 68-year-old male. Despite the patient's previous history of left nephrectomy, no significant pathological findings were initially observed. The bladder lipoma was detected via cystoscopy as a polypoid mass on the posterior bladder wall and confirmed through transurethral resection of the bladder tumor (TUR-BT). Histopathological analysis verified the mass as a bladder lipoma composed of mature adipocytes. Following a specific postoperative follow-up period, no recurrence of the tumor was observed, suggesting successful treatment. This case underscores the clinical significance of considering bladder lipoma in differential diagnoses of bladder tumors, especially in patients presenting with gross hematuria, given its exceptional rarity.

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Paraganglioma of the Urinary Bladder: A Case Report on a Rare and Unexpected Tumor Location

Cited by 3 publications

References 15 publications

Bladder Paraganglioma Presenting as Post-Micturition Palpitations: A Case Report

Bladder Paraganglioma Presenting as Post-Micturition Palpitations: A Case Report

Paraganglioma of the urinary bladder- a case report

An Atypical Case of Bladder Lipoma Presenting as Gross Hematuria: A Case Report

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